Publications by authors named "Patrick Judson Blatchford"
Ann Surg Oncol
March 2018
Article Synopsis
- Desmoid fibromatosis is a type of tumor linked to mutations in the WNT pathway, and a study was conducted to evaluate the oral gamma secretase inhibitor PF-03084014 for treatment.
- In a small cohort of seven patients, 71.4% achieved a partial response to the treatment, with most maintaining their response for extended periods even after stopping the medication.
- The study concluded that PF-03084014 is effective and well-tolerated, showing significant disease control, particularly at lower doses.
