Use of Real-World Evidence in Health Technology Reassessments Across Six Health Technology Assessment Agencies.

Objectives: To review health technology assessment reassessments (HTARs) and characterize the use of real-world evidence (RWE) in HTARs.

Methods: Six agencies were chosen for inclusion in this targeted review: CADTH, NICE, HAS, G-BA/IQWiG, ZIN, and PBAC. Each agency's assessments were screened to identify their eight most recent HTARs, which were evaluated to determine if they used RWE.