A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.

Background: There are no population-based data comparing analgesics after Mohs micrographic surgery (MMS) and reconstruction. OBJECTIVE To compare the efficacy in pain management of three analgesic combinations.

Methods: In a randomized, double-blind, controlled study, patients undergoing MMS and reconstruction for head and neck skin cancers received 1,000 mg of acetaminophen (Ac), 1,000 mg Ac plus 400 mg ibuprofen (Ib), or 325 mg Ac plus 30 mg codeine (Co) immediately after surgery and every 4 hours for up to four doses.

A randomized controlled trial of high-viscosity 2-octyl cyanoacrylate tissue adhesive versus sutures in repairing facial wounds following Mohs micrographic surgery.

Background: High-viscosity 2-octyl cyanoacrylate (HVOCA) is a rapidly polymerizing liquid topical adhesive indicated for epidermal approximation of superficial lacerations and surgical wounds. Use of HVOCA in repair of facial wounds after Mohs micrographic surgery (MMS) has not been reported.

Objective: To compare aesthetic outcome of HVOCA versus sutured epidermal closure of linearly repaired facial wounds following MMS.

Rickettsia parkeri infection after tick bite, Virginia.

We describe a man with a febrile illness and an eschar that developed at the site of a tick bite. Rickettsia parkeri was detected and isolated from the eschar. This report represents the second documented case of R.

Stevens-Johnson syndrome induced by doxycycline.

Stevens-Johnson syndrome (SJS) is an acute mucocutaneous eruption nosologically related to erythema multiforme (EM) and toxic epidermal necrolysis (TEN). Medications are the most common triggering factors for SJS, with anticonvulsants, sulfonamides, penicillins, allopurinol, and nonsteroidal anti-inflammatory drugs (NSAIDs) most commonly implicated. SJS is very rarely associated with tetracyclines.

Distribution of toenail dystrophy predicts histologic diagnosis of onychomycosis.

Background: Onychomycosis (OM) affects up to 10% of the general population and is associated with functional impairment. Clinically, OM can mimic nail psoriasis, trauma, lichen planus, oncyhogryphosis, and other disorders. Laboratory methods for diagnosing OM vary in accuracy and predictive value.

Treatment of granuloma annulare with the 585 nm pulsed dye laser.

Background: Granuloma annulare is a chronic asymptomatic dermatosis that is typically manifested by annular papules arising on the dorsa of the hands, feet, elbows, and knees. Multiple treatment modalities have been used with variable efficacy, but no known cure exists. Obtaining long-term resolution of involved areas is often a therapeutic challenge.

Guiding sutures to promote optimal contraction of a large surgical defect prior to delayed grafting.

Background: Large surgical defects on the face are often challenging to repair.

Objective: To describe a method to reduce wound area and promote wound contraction.

Materials And Methods: Case report.

Rapidly growing mycobacterial infections after pedicures.

Background: Rapidly growing mycobacteria (RGM) can cause a variety of cutaneous and systemic diseases. The causative organisms are typically Mycobacterium fortuitum or Mycobacterium chelonae (also known as Mycobacterium abscessus). Primary cutaneous lesions may develop after a variable latent period, from weeks to several months, and usually result from direct inoculation after trauma, from injections, or during surgery via contaminated medical instruments.