The endoscope as an adjunct to correction of nipple inversion deformity.

Background: Correction of the inverted nipple requires release of constricting fibrous tissue and suspension of the nipple. Despite the simplicity, lasting repair is often difficult to achieve, as is the ability to assure preservation of functioning lactiferous ducts during release.

Methods: Since 2002, the authors have used the endoscope to guide selective division of retracted fibrous bands, followed by the use of a dermal fat graft and purse-string suture to the base to achieve stable nipple projection.

The effects of anti-P-selectin antibody on leucocyte activity related to cigarette smoke in rats.

Nicotine-induced expression of P-selectin is implicated in endothelial cell damage related to smoking. Thirty male Sprague-Dawley rats were divided into three groups: two experimental and one control. Both experimental groups were exposed to cigarette smoke for four weeks, but one group was also given anti-P-selectin antibody (100 microg IgG per 100 g body weight) intravenously.