Background: Growth hormone (GH)--secreting pituitary adenomas can be aggressive and difficult to manage. Surgical resection for GH-secreting tumors remains the gold standard with increasing use of expanded endoscopic endonasal (EEA) techniques. Certain anatomical considerations make postsurgical biochemical remission challenging.
View Article and Find Full Text PDFWe present the case of a 16-year-old with short stature, fatigue, memory impairment, and pituitary gland failure. Imaging and cerebrospinal fluid (CSF) studies supported the diagnosis of a suprasellar nongerminomatous germ cell tumor with no clear radiologic disease in the spine; however, a single atypical cell was present in the CSF. After a period of external drainage via an Ommaya device, he was treated with chemotherapy, followed by craniospinal radiation.
View Article and Find Full Text PDFBackground: Thyrotropinomas (TSHoma) are rare pituitary adenomas.
Case Description: A 34-year-old female presented with mild bitemporal field defect in third trimester with intact pituitary function. MRI demonstrated an enhancing lesion from the posterior planum to suprasellar, interpeduncular and prepontine cisterns with chiasmal compression and right fetal posterior communicating artery encasement.
Suprasellar hemangioblastomas are rare lesions occurring sporadically or more commonly with von Hippel Lindau disease (VHLD).1,2 A 27-yr-old female presented with amenorrhea, mildly raised prolactin levels and otherwise normal pituitary function, homonymous hemianopia, and mild cognitive decline. Imaging revealed a large suprasellar lesion arising from the infundibulum, causing compression of optic chiasm with edema in the visual pathways.
View Article and Find Full Text PDFIn this paper five multivariable adaptive and classical control strategies have been studied and implemented in a simulator of the copper grinding plant of CODELCO-Andina. The strategies presented were compared and, according to theory, exhibit good behavior. The extended horizon, pole-placement and model reference multivariable adaptive control strategies were formulated in discrete-time and use a model of the plant whose parameters are updated on line using the recursive least squares method along with UD factorization of the covariance matrix and variable forgetting factor.
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