Publications by authors named "Patricia de Cassia Salgado"
Differential expression of genes related to calcineurin and mTOR signaling and regulatory miRNAs in peripheral blood from kidney recipients under tacrolimus-based therapy.
Vivian Bonezi Fabiana Dalla Vecchia Genvigir Patrícia de Cássia Salgado Claudia Rosso Felipe Helio Tedesco-Silva
Ann Transl Med
September 2020
Background: Genetic and epigenetics factors have been implicated in drug response, graft function and rejection in solid organ transplantation. Differential expression of genes involved in calcineurin and mTOR signaling pathway and regulatory miRNAs was analyzed in the peripheral blood of kidney recipient cohort (n=36) under tacrolimus-based therapy.
Methods: , , , , and mRNA expression and polymorphisms in and were analyzed by qPCR.