Hepatic damage in newborns from female rats exposed to the pesticide derivative ethylenethiourea.

Purpose: To evaluate hepatic morphological-histological abnormalities in newborns from female rats exposed to ethylenethiourea.

Methods: A randomized study was conducted on fifty-five newborn Wistar rats were studied: 34 in the experimental group, whose mothers had been exposed to 1% ethylenethiourea; and 21 in the control group, whose mothers had received 0.9% physiological solution.

Abnormalities of digestive tract innervation in rat fetus treated with ethylenethiourea.

Purpose: The pathophysiology of abnormalities associated with myenteric plexus lesions remains imperfectly understood. Such abnormalities have been correlated with subocclusive intestinal conditions in children with Hirschsprung's disease, cases of chronic constipation and, postoperatively, in cases of anorectal anomalies. This study evaluated abnormalities of the myenteric plexus in fetus from female rats that received ethylenethiourea.