Markerless motion analysis to assess reaching-sideways in individuals with dyskinetic cerebral palsy: A validity study.

This study aimed to evaluate clinical utility of 2D-markerless motion analysis (2DMMA) from a single camera during a reaching-sideways-task in individuals with dyskinetic cerebral palsy (DCP) by determining (1) concurrent validity by correlating 2DMMA against marker-based 3D-motion analysis (3DMA) and (2) construct validity by assessing differences in 2DMMA features between DCP and typically developing (TD) peers. 2DMMA key points were tracked from frontal videos of a single camera by DeepLabCut and accuracy was assessed against human labelling. Shoulder, elbow and wrist angles were calculated from 2DMMA and 3DMA (as gold standard) and correlated to assess concurrent validity.

Age- and sex-related differences in trunk kinematics during walking in able-bodied adults.

Introduction: Trunk motion during walking acts as a biomarker for decreased mobility and can differ between sexes. Knowing how age and sex affect trunk motion and energy conservation can help clinicians decide when and in whom to intervene with physiotherapy to prolong functional mobility.

Methods: A large sample of 138 able-bodied males and females in the age-categories 20-39 years, 40-59 years, 60-69 years, 70-79 years, and 80-89 years received a full-body 3D gait analysis.

Gait Stride Length Estimation Using Embedded Machine Learning.

Introduction: Spatiotemporal gait parameters, e.g., gait stride length, are measurements that are classically derived from instrumented gait analysis.

Functional mobility in children and young adults with Dravet syndrome.

Aim: This cohort study aimed to describe functional mobility in Dravet syndrome, a developmental and epileptic encephalopathy.

Method: Functional mobility was assessed in individuals (aged 3-25 years), diagnosed with Dravet syndrome, using the Functional Mobility Scale (FMS), Mobility Questionnaire 28 (MobQues28), and estimated walking distance. Secondary outcome variables were Gait Profile Score (GPS), walking velocity, age at independent walking, intellectual disability, seizure frequency, genetic variant type, and body mass index (BMI).

Instrumented strength assessment in typically developing children and children with a neural or neuromuscular disorder: A reliability, validity and responsiveness study.

The aim of this study was to determine the clinimetric properties, i.e., reliability, validity and responsiveness of an instrumented strength assessment in typically developing (TD) children and children with cerebral palsy (CP) and Duchenne muscular dystrophy (DMD).

Strength measurements in patients with Dravet Syndrome.

Background: Dravet Syndrome (DS) is a developmental and epileptic encephalopathy, characterized by drug resistant infantile onset seizures and cognitive and motor impairment. Walking problems progressively occur and crouch gait is frequently observed. Muscle weakness is hypothesized as contributing impairment.

The mechanics behind gait problems in patients with Dravet Syndrome.

Background: Dravet Syndrome (DS) is a developmental and epileptic encephalopathy starting in infancy and characterised by treatment resistant epilepsy with cognitive impairment and progressive motor dysfunction. Walking becomes markedly impaired with age, but the mechanical nature of gait problems remains unclear.

Research Question: What are the kinetic strategies characterised in gait of patients with DS?

Methods: This case-control study compared 41 patients with DS aged 5.

Foot-floor contact pattern in children and adults with Dravet Syndrome.

Background: Dravet Syndrome (DS) is a developmental and epileptic encephalopathy characterized by severe drug-resistant seizures and associated with cognitive and motor impairments. Walking problems are frequently observed. As the foot plays a key role during walking, compromised foot function can be a feature of deviant gait.

Independent walking and cognitive development in preschool children with Dravet syndrome.

Aim: To investigate the relation between cognitive and motor development in preschool aged children with Dravet syndrome, in particular between the age of independent walking and cognitive development.

Method: Results of cognitive and motor developmental assessments and the age of independent walking were retrieved retrospectively from the medical records of 33 children (17 males, 16 females; mean age at last evaluation 33.2mo, SD 8.

Motor functions.

Motor development includes the evolution from reflexive to voluntary and goal-directed motor actions. These motor actions are never performed in isolation but always in a varying physical environment, often requiring object and social interaction. For a child to function within this context, they require the ability to demonstrate skillful, efficient, and voluntary postures and movement patterns.

Age-related differences in interlimb coordination during typical gait: An observational study.

Background: Arm movements during gait are known to alter with increasing age during the slow maturation phase (>3years). It is unclear whether coordination between the arms and legs (i.e.

Trunk biomechanics during walking after sub-acute stroke and its relation to lower limb impairments.

Background: Trunk function and lower limb strength seem to be the primary predictors for functional independence in acute stroke patients. Gaining a better understanding of their relationship during walking aids in the identification of intrinsic trunk control deficits and underlying lower limb deficits resulting in compensatory trunk movements.

Methods: Fifty-seven subjects with stroke and 57 age- and gender-matched subjects without disability were included.

Gait abnormalities in people with Dravet syndrome: A cross-sectional multi-center study.

Objective: To quantify gait abnormalities in people with Dravet syndrome (DS).

Methods: Individuals with a confirmed diagnosis of DS were enrolled, and stratified according to knee flexion at initial contact (IC) and range of motion (ROM) during stance (atypical crouch: knee flexion >20° at IC and knee ROM >15° during stance; straight: knee flexion <20° at IC). A 1D ANOVA (α = 0.

Gait deviations in patients with dravet syndrome: A systematic review.

Background: Dravet Syndrome is a rare developmental and epileptic encephalopathy characterised by epileptic seizures, cognitive impairment and motor disorders. Gait is markedly impaired and could benefit from targeted intervention to improve quality of life for patient and caregivers.

Objective: To establish the state of the art regarding gait deviations in patients with Dravet Syndrome.

Motor development in children with Dravet syndrome.

Aim: The aim of this study is to describe the course of motor development in children with Dravet syndrome.

Method: Forty-three participants (21 males, 22 females; mean age at last assessment 53.89mo±42.

Age-related changes in arm motion during typical gait.

Background: When toddlers learn to walk, they do so with a typical high guard position of the arms. As gait matures, children develop a reciprocal arm swing. So far, there have been no attempts to describe age-related changes of arm movements during walking after this first rapid development.

Age-related differences in muscle activity patterns during walking in healthy individuals.

Objective: To examine how muscle activity over the entire gait cycle changes with increasing age.

Methods: Electromyography data of the erector spinae, rectus femoris, vastus lateralis, biceps femoris, tibialis anterior and gastrocnemius muscles were collected by an instrumented gait analysis during over ground walking in healthy adults aged between 20 and 89 years. Participants were categorized per decade (n = 105, 15 per decade, decades 3-9).

Effectiveness of additional trunk exercises on gait performance: study protocol for a randomized controlled trial.

Background: Evidence is lacking concerning the effect of additional trunk rehabilitation on gait performance. Investigating gait performance by both clinical and biomechanical outcome measures might lead to new scientific insights into the importance of the trunk during gait rehabilitation in people suffering from stroke. This protocol was written according to the SPIRIT 2013 Statement.

Coordinating arms and legs on a hybrid rehabilitation tricycle: the metabolic benefit of asymmetrical compared to symmetrical arm movements.

Purpose: The most commonly used propulsion method for handcycling is moving the arms symmetrically. Previous studies indicated that during outdoor handcycling symmetrical arm movements are more efficient. During locomotor movements, however, arm movements are performed asymmetrically in combination with leg movements.

How can push-off be preserved during use of an ankle foot orthosis in children with hemiplegia? A prospective controlled study.

Several studies indicated that walking with an ankle foot orthosis (AFO) impaired third rocker. The purpose of this study was to evaluate the effects of two types of orthoses, with similar goal settings, on gait, in a homogeneous group of children, using both barefoot and shoe walking as control conditions. Fifteen children with hemiplegia, aged between 4 and 10 years, received two types of individually tuned AFOs: common posterior leaf-spring (PLS) and Dual Carbon Fiber Spring AFO (CFO) (with carbon fibre at the dorsal part of the orthosis).

Do dynamic and static clinical measurements correlate with gait analysis parameters in children with cerebral palsy?

The present study documents the correlation between gait analysis data and clinical measurements and evaluates the combined predictive value of static and dynamic clinical measurements on gait data of children with cerebral palsy. Two hundred patients were evaluated using a set of measurements of range of motion (ROM), alignment, spasticity, strength and selectivity, and by three-dimensional gait analysis. Fair to moderate correlations were found between clinical measurements and gait data, the overall highest correlation being 0.