Publications by authors named "Patricia V C Bettega"

Early childhood caries (ECC) is a global problem, disproportionately affecting disadvantaged populations. The aim of this study was to evaluate systematically the available scientific evidence on the effectiveness of methods for ECC prevention. Six electronic databases were searched.

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Purpose: Subepithelial connective tissue grafts (SCTGs) are commonly performed for the treatment of gingival recession due to their high predictability. This study evaluated and histologically compared connective tissue grafts in terms of the presence of epithelial remnants and composition of the tissue types that were present (epithelium, lamina propria, and submucosa).

Methods: Ten patients underwent epithelium removal using 2 different techniques: the use of a blade (group B) and through abrasion (group A).

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  • A survey conducted in 100 gyms in Curitiba involving 5773 individuals aimed to assess the use of anabolic steroids (AS) among resistance trainers.
  • The results showed that 83.2% of respondents did not use AS, while 16.9% of men and 6.5% of women had either used or intended to use them, with male users significantly outnumbering female users.
  • The findings suggest that a gym's environment fosters AS use for aesthetic reasons, highlighting the need for preventive measures targeting younger, university-educated, and single gym-goers who train longer.
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Objective: To compare the use of anabolic steroids (AS), the motivation to use them, their side effects, the source of information and the form in which AS were obtained, the medical follow-up, and the periodic examinations in resistance training practitioners who are either current or former users of AS.

Methods: A prevalence survey was performed in the gyms of the city of Curitiba, including 719 current and former AS users who self-administered a questionnaire. The chi-square and z of proportions (p <0.

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  • The study analyzed profiles of polytraumatized ICU patients, focusing on serum and salivary biomarker comparisons between two APACHE II classes during their hospitalization.
  • Key findings included changes in blood and saliva markers, particularly regarding pH, creatinine, urea, glucose, and calcium, with Class II showing distinct trends compared to Class I over time.
  • The research suggests that monitoring both salivary and serum biomarkers effectively tracks the clinical status of ICU patients, highlighting the correlation between these two types of markers.
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  • The study evaluated apoptosis in the parotid glands of Wistar rats treated with midazolam, with some groups also receiving pilocarpine.
  • Results indicated that rats treated with midazolam alone exhibited a significantly higher apoptotic index compared to control groups treated with saline.
  • The addition of pilocarpine reduced the apoptotic effects caused by midazolam, suggesting it may offer some protective benefits against cell death in the glands.
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Benzodiazepines (BZDs), the most commonly prescribed psychotropic drugs with anxiolytic action, may cause hyposalivation. Therefore, this study sought to quantify the acini (N) in parotid glands of Wistar rats treated chronically with two BZDs (Lorazepam and Midazolan) and to verify the action of the pilocarpine when administered with these drugs. Ninety male Wistar rats were distributed in 9 groups according to the administration of: a) S30 - saline solution for 30 days; b) S60 - saline solution for 60 days; c) P60 - pilocarpine for 60 days; d) L30 - Lorazepam for 30 days; e) M30 - Midozolam for 30 days; f) LS60 - Lorazepam for 60 days and, after this period, 30 more days of saline solution; g) MS60 - Midazolam for 30 days and, after this period, 30 more days of saline solution; h) LP60 - Lorazepam and Pilocarpine for 60 days; i) MP60 - Midazolam and Pilocarpine for 60 days.

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Oral lesions that manifest as ulcer lesions are quite common and can cause discomfort to the patient. Searching for drugs to accelerate the healing of these lesions is nonstop process. Bixin is a molecule found in annatto (urucum) seeds and is considered a viable therapeutic option to treat such lesions due to its anti-inflammatory, anti-oxidant, and healing properties.

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