Publications by authors named "Patricia Tauran"
The burden of antimicrobial-resistant (AMR) infections in low and middle-income countries (LMICs) is largely unknown. Here, we evaluate attributable mortality of AMR infections in Indonesia. We used routine databases of the microbiology laboratory and hospital admission at Dr.
View Article and Find Full Text PDFBlood culturing remains the "gold standard" for bloodstream infection (BSI) diagnosis, but the method is inaccessible to many developing countries due to high costs and insufficient resources. To better understand the utility of blood cultures among patients in Indonesia, a country where blood cultures are not routinely performed, we evaluated data from a previous cohort study that included blood cultures for all participants. An acute febrile illness study was conducted from July 2013 to June 2016 at eight major hospitals in seven provincial capitals in Indonesia.
View Article and Find Full Text PDFBackground: Chikungunya virus (CHIKV) is often overlooked as an etiology of fever in tropical and sub-tropical regions. Lack of diagnostic testing capacity in these areas combined with co-circulation of clinically similar pathogens such as dengue virus (DENV), hinders CHIKV diagnosis. To better address CHIKV in Indonesia, an improved understanding of epidemiology, clinical presentation, and diagnostic approaches is needed.
View Article and Find Full Text PDFArticle Synopsis
- - A modeling study suggests Indonesia may have up to 20,000 cases of melioidosis annually, leading to around 10,000 deaths, though the actual situation remains unclear.
- - Researchers reviewed 146 confirmed cases, mainly from Java, and found a significant misidentification issue; the mortality rate in recent cases was recorded at 43%.
- - A survey indicated that over half of healthcare workers were unaware of melioidosis, highlighting the need for increased awareness, improved culture usage, and precise diagnosis to manage the disease effectively.
Article Synopsis
- Sepsis patients should ideally have two blood cultures taken before starting antibiotic treatment to ensure effective management.
- From 1995 to 2015, blood culture tests at a hospital in Thailand significantly increased, indicating a higher testing rate compared to a hospital in Indonesia, which had a much lower sampling rate in 2015.
- Inadequate use of blood cultures can result in underestimating the prevalence of antimicrobial-resistant infections, highlighting the need for improved lab capabilities in developing countries.
Melioidosis is known to be highly endemic in parts of southeast Asia and northern Australia; however, cases are rarely reported in Indonesia. Here we report three cases of melioidosis in Makassar, South Sulawesi, Indonesia occurring between 2013 and 2014. Two patients died and the other was lost to follow-up.
View Article and Find Full Text PDF