Publications by authors named "Patricia Rolim"
Article Synopsis
- Rheumatoid arthritis (RA) is linked to genetic factors, particularly involving immune response components and specific cytokines related to its onset.
- This study focuses on the MYD88 gene variant rs6853 and its impact on RA severity, examining blood samples from 423 RA patients and 346 control individuals in Brazil.
- Results indicate that the A allele and AA genotype increase RA risk, with lower MYD88 mRNA levels and higher IL-1β production observed in specific cell culture conditions.
