Publications by authors named "Patricia Rigou"
Article Synopsis
- The nuclear factor Acinus is involved in apoptosis, but recent evidence indicates it also plays a role in DNA fragmentation during this process.
- The survival protein AAC-11 binds to Acinus, preventing its function in DNA cleavage and thus protecting cells from apoptosis, especially in low growth factor conditions.
- Targeting AAC-11 can enhance the effectiveness of cancer drugs by increasing cancer cell sensitivity to treatment, suggesting it could be a strategic target for improving chemotherapy outcomes.
