Publications by authors named "Patricia Rantshabeng"
Article Synopsis
- Cervical cancer continues to be a significant public health challenge in Botswana, particularly among indigenous and marginalized groups, despite the introduction of a quadrivalent HPV vaccine and screening initiatives.
- A study involving 171 non-HPV vaccinated women aged 21 and older assessed the prevalence of high-risk HPV genotypes and cervical lesions through interviews, Pap smears, and HPV testing.
- The results revealed that 31% of participants were HIV positive, and 13.5% exhibited cervical dysplasia, with various atypical cell types identified, although no cases of high-grade lesions or cervical cancer were found.
Article Synopsis
- Cervical cancer, often caused by oncogenic human papillomavirus (HPV), primarily impacts women in low-resource areas, particularly those from marginalized indigenous communities in Botswana.
- A study involving 171 women found that current smokers were nearly twice as likely to have high-risk HPV infections compared to non-smokers, with a significant portion also living with HIV.
- The results highlight the urgent need for targeted tobacco control measures to reduce cervical cancer risks in these communities.
Background: High-risk human papillomavirus (HR-HPV) has been demonstrated to be the necessary cause of cervical carcinoma. High-risk HPV detection has a prognostic significance for the women who are at increased risk of disease progression. HPV genotyping in cervical cancer precursor lesions is crucial for prevention and management of cervical cancer.
View Article and Find Full Text PDFBackground: Human papillomavirus (HPV) associated malignancies are the leading cause of cancer death in Botswana. We sought to determine causative HPV types in patients with anogenital malignancies in Botswana to inform vaccine strategy.
Methods: We used formalin-fixed and paraffin-embedded (FFPE) tissue blocks from patients diagnosed with anal, penile and vulvar squamous cell carcinomas between the years, 2014 and 2016.