Publications by authors named "Patricia P Viola"

Article Synopsis
  • DUIC cases are on the rise globally, making effective methods for cannabis detection crucial as THC is the second most common drug involved in impaired driving after alcohol.
  • A study tested four oral fluid devices for THC detection at roadside checks, revealing significant differences in their effectiveness: Dräger DrugTest® performed best, while AquilaScan® and Druglizer® had poor performance.
  • The findings stress the importance of using reliable testing devices to ensure public safety, given the high occurrence of cannabis use among drivers.
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Introduction: We analyzed the prevalence of non-small-cell lung cancer (NSCLC) with a programmed cell death ligand 1 (PD-L1) tumor proportion score (TPS) of ≥ 50% and compared the results with the existing data from clinical trials and databases from other countries.

Materials And Methods: The Latin American Cooperative Oncology Group and Grupo Brasileiro de Oncologia Torácica performed a retrospective, cross-sectional study from August 2017 to April 2018. PD-L1 expression was collected from pathology reports from 5 laboratories in Brazil.

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Warfarin is an oral anticoagulant prescribed to prevent and treat thromboembolic disorders. It has a narrow therapeutic window and must have its effect controlled. Prothrombin test, expressed in INR value, is used for dose management.

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Phenprocoumon is widely used in prophylaxis and treatment of thromboembolic disorders. However, its pharmacokinetics and pharmacodynamics vary according to several genetic and non-genetic factors. Phenprocoumon metabolism is mediated by CYP2C9 and CYP3A enzymes.

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