Publications by authors named "Patricia N P Ip"

Objective: To evaluate the performance of maternal factors, biophysical and biochemical markers at 11-13 + 6 weeks' gestation in the prediction of gestational diabetes mellitus with or without large for gestational age (GDM ± LGA) fetus and great obstetrical syndromes (GOS) among singleton pregnancy following in-vitro fertilisation (IVF)/embryo transfer (ET).

Materials And Methods: A prospective cohort study was conducted between December 2017 and January 2020 including patients who underwent IVF/ET. Maternal mean arterial pressure (MAP), ultrasound markers including placental volume, vascularisation index (VI), flow index (FI) and vascularisation flow index (VFI), mean uterine artery pulsatility index (mUtPI) and biochemical markers including placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) were measured at 11-13 + 6 weeks' gestation.

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  • Intrauterine adhesion (IUA) can occur after uterine surgeries, leading to complications during miscarriage management, and this study aimed to compare IUA rates between ultrasound-guided manual vacuum aspiration (USG-MVA) and electric vacuum aspiration (EVA) in women experiencing first-trimester miscarriage.
  • Conducted as a randomized controlled trial at a tertiary hospital, this study involved 303 Chinese women who underwent either USG-MVA or EVA, with follow-up assessments to evaluate IUA occurrence between 6 and 20 weeks post-surgery.
  • Results revealed that the IUA incidence was significantly lower in the USG-MVA group (19.0%) compared to the EVA group (32.0%), highlighting
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  • Ultrasound-guided manual vacuum aspiration (USG-MVA) proves to be a safe and effective outpatient option for treating early pregnancy loss, compared to electric vacuum aspiration (EVA).
  • In a study with 292 women, those who underwent EVA showed a significantly higher incidence of intrauterine adhesion (IUA), implying that USG-MVA may pose lower risks of complications.
  • Follow-up results indicated no significant differences in reproductive outcomes between the two methods, with fewer women experiencing hypomenorrhea after USG-MVA.
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Ovarian stimulation is a fundamental step in assisted reproductive technology (ART) with the intention of inducing ovarian follicle development prior to timed intercourse or intra-uterine insemination and facilitating the retrieval of multiple oocytes during a single in vitro fertilization (IVF) cycle. The basis of ovarian stimulation includes the administration of exogenous gonadotropins, with or without pre-treatment with oral hormonal therapy. Gonadotropin-releasing hormone agonist or antagonist is given in addition to the gonadotropins to prevent a premature rise of endogenous luteinizing hormone that would in turn lead to premature ovulation.

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Objectives: To assess clinical utility of the urine Congo red dot test (CRDT) in predicting composite adverse maternal and neonatal outcomes in women with suspected preeclampsia (PE).

Methods: CRDT result and pregnancy outcomes were prospectively documented in women with new onset or pre-existing hypertension, new or pre-existing proteinuria, PE symptoms and suspected PE-related fetal growth restriction or abnormal Doppler presenting from 20 weeks' gestation between January 2020 and December 2022. Participants and clinicians were blinded to the CRDT result and managed according to internally agreed protocols.

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Objectives: To evaluate the diagnostic performance and clinical utility of the urine Congo red dot test (CRDT) in predicting preeclampsia (PE) within 7 days, 14 days and 28 days of assessment.

Study Design: A prospective single center double blind non-intervention study conducted from January 2020 to March 2022. Urine congophilia has been proposed as a point-of-care test for the prediction and rapid identification of PE.

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