Detection of SARS-CoV-2 Virus on Stainless-Steel Surfaces: AOAC Performance Tested MethodSM 022102.

Background: The SureFast® SARS-CoV-2 PLUS Test is a reverse transcription qPCR (RT-qPCR) assay for the direct, qualitative detection of novel coronavirus (SARS-CoV-2) RNA from stainless-steel environmental sample swabs.

Objective: To validate the SureFast SARS-CoV-2 PLUS Kit as part of the AOAC Research Institute's Emergency Response Validation Performance Tested Method(s)SM program.

Method: The SureFast SARS-CoV-2 PLUS Kit was evaluated for specificity using in silico analysis of 15 764 SARS-CoV-2 sequences and 65 exclusivity organisms (both near neighbors and background organisms) using the ThermoBLAST program.

Validation of the R-Biopharm AG RIDASCREEN® Histamine (Enzymatic) Kit.

Background: RIDASCREEN® Histamine (enzymatic) is an enzymatic test kit for quantification of histamine in fresh fish, canned fish, fish meal, cheese, and wine.

Methods: Fish products are extracted with boiling water, while cheese is extracted with water, and the extract is treated with perchloric acid/potassium hydroxyde. Wine is extracted with the reagents of RIDA® Sample Decolorant kit to eliminate color pigments and interfering compounds.

Recognizing waterborne disease and the health effects of water contamination: a review of the challenges facing the medical community in the United States.

Preservation of water quality and prevention of waterborne disease is a complicated task requiring a coordinated effort from many diverse disciplines including physicians, healthcare providers, epidemiologists, microbiologists, academic scientists, science researchers, local and national health authorities, public and environmental health specialists, water engineers and water purveyors. Any successful strategy to ensure water quality and safety in the United States must include the medical community as a valued stakeholder and active participant in this ongoing public health challenge. Unfortunately, the majority of practicing healthcare providers in the US has received limited training in the recognition and evaluation of water-related disease and faces many significant challenges and numerous barriers to diagnosing waterborne disease and the health effects of water pollution in their patients.

Water and bioterrorism: preparing for the potential threat to U.S. water supplies and public health.

Water supplies and water distribution systems represent potential targets for terrorist activity in the United States because of the critical need for water in every sector of our industrialized society. Even short-term disruption of water service can significantly impact a community, and intentional contamination of a municipal water system as part of a terrorist attack could lead to serious medical, public health, and economic consequences. Most practicing physicians and public health professionals in the United States have received limited training in the recognition and evaluation of waterborne disease from either natural or intentional contamination of water.

Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation.

Purpose: To study safety, feasibility, and biologic activity of adenovirus-mediated p53 gene transfer in patients with bladder cancer.

Patients And Methods: Twelve patients with histologically confirmed bladder cancer scheduled for cystectomy were treated on day 1 with a single intratumoral injection of SCH 58500 (rAd/p53) at cystoscopy at one dose level (7.5 x 10(11) particles) or a single intravesical instillation of SCH 58500 with a transduction-enhancing agent (Big CHAP) at three dose levels (7.