[The 2024 landscape of aldosterone blockade].

Aldosterone is a steroid hormone playing a key role in arterial hypertension physiopathology. In case of inappropriate secretion, it has a detrimental action on the kidney and cardiovascular system and therefore constitutes an interesting therapeutic target for several diseases. Recent progress allowed to expand the therapeutic arsenal for physician practitioner and new promising drugs will probably appear on the market the next few years.

[Surgical treatment for primary aldosteronism].

Primary aldosteronism is the most common cause of secondary hypertension in the middle-aged population. A high level of suspicion is required, due to the higher morbidity and mortality associated with damage to target organs (heart, brain, vessels, kidneys) than with essential hypertension. Screening involves 3 phases: detection, confirmation and detection of lateralization if surgery is an option.

Inferior vena cava thrombosis as a possible cause of nephrotic-range proteinuria: two case reports.

Background: Nephrotic-range proteinuria is a common reason for nephrological consultation in clinical practice. The differential diagnosis is wide, and generally focuses on different forms of glomerulonephritis, but other causes should not be overlooked, as illustrated in this article.

Case Presentations: We report two female patients with nephrotic-range proteinuria.

[Gender differences in chronic kidney diseases : myth or reality ?].

Chronic kidney disease (CKD) concerns about 10 % of the population in Switzerland. Epidemiological studies suggest that women are less prone to the development of CKD than men, and progress less rapidly to end stage renal disease. This protection seems lost when entering menopause.