Publications by authors named "Patricia Martins Goncalves"
Synthesis and evaluation of esters obtained from phenols and phenoxyacetic acid with significant phytotoxic and cytogenotoxic activities.
Patrícia Fontes Pinheiro Geisiele Silva Martins Patrícia Martins Gonçalves Loren Cristina Vasconcelos Aline Dos Santos Bergamin
Environ Sci Pollut Res Int
October 2024
Article Synopsis
- There is an increasing need for herbicides that are both effective and environmentally friendly, prompting a study on synthesizing new compounds from phenols and phenoxyacetic acid.
- The research involved creating seven esters through a specific chemical reaction and characterizing them using advanced techniques, followed by testing their effects on seed germination and root development of two plant species.
- Results indicated that some esters showed significant phytotoxic effects and caused noticeable damage at the cellular level in one of the plants, suggesting their potential use in developing new herbicides.
Semisynthetic phenol derivatives were obtained from the natural phenols: thymol, carvacrol, eugenol, and guaiacol through catalytic oxychlorination, Williamson synthesis, and aromatic Claisen rearrangement. The compounds characterization was carried out by H NMR, C NMR, and mass spectrometry. The natural phenols and their semisynthetic derivatives were tested for their antimicrobial activity against the bacteria: Staphylococcus aureus, Escherichia coli, Listeria innocua, Pseudomonas aeruginosa, Salmonella enterica Typhimurium, Salmonella enterica ssp.
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