Rebiopsy in patients with untreated hepatitis C: a useful procedure.

Background: The progression of fibrosis in the early stages of chronic hepatitis C virus is variable, and the ideal interval to perform a new biopsy in untreated patients is still unknown.

Aims: We evaluated the histologic progression of patients with untreated hepatitis C virus with two liver biopsies and correlated disease progression with demographic, epidemiologic, biochemical, and histologic variables.

Patients And Methods: Untreated hepatitis C virus-infected patients with two liver biopsies at a minimum interval of 1 year were studied.