Cytotoxicity and cytokine expression induced by silorane and methacrylate-based composite resins.

Objective: The aim of this study was to evaluate cytotoxicity and cytokine production induced by light-cured or non-light-cured methacrylate-based and silorane composite resins in RAW 264.7 macrophages.

Material And Methods: Cells were stimulated with the extracts from light-cured or non-light-cured composite resins.

Expression of Mineralization Markers during Pulp Response to Biodentine and Mineral Trioxide Aggregate.

Introduction: The purpose of this study was to compare the cell viability of dental pulp cells treated with Biodentine (Septodont, Saint-Maur, France) and mineral trioxide aggregate (MTA) and the in vitro and in vivo expression of mineralization markers induced by the 2 materials.

Methods: Human dental pulp cells isolated from 6 permanent teeth were stimulated with Biodentine and MTA extracts. Cell viability was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay, and quantitative reverse-transcriptase polymerase chain reaction was used to determine the expression of mineralization markers.