Myocardial perfusion and ventricular function assessed by SPECT and Gated-SPECT in end-stage renal disease patients before and after renal transplant.

Background: Cardiovascular disease is a major cause of morbidity and mortality in end-stage renal disease (ESRD). Renal transplant is known to improve left ventricle hypertrophy and systolic dysfunction in selected groups of patients.

Methods: We assessed myocardial perfusion, wall motion and functional parameters by single photon emission computed tomography (SPECT) and Gated-SPECT in 30 consecutive ESRD patients with normal coronary angiograms before and after renal transplantation.