Publications by authors named "Patricia Kink"
The treatment of female urethral stricture disease is in flux in terms of developing guidelines for surgical treatment. Urethral strictures in women are rare, but frequently result because of urethral instrumentation or surgery. Stricture sites vary from proximal, intrasphincteric, distal or at the meatus.
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- * In a study of 152 patients with solid tumors, over half were anemic and reported higher levels of depression and poorer QoL, experiencing fatigue and social difficulties.
- * The research highlights a connection between immune activation, diminished tryptophan levels, and the psychological well-being of cancer patients, suggesting that addressing anemia could improve overall health outcomes.
Many patients with cancer suffer from anemia, depression, and an impaired quality of life (QoL). These patients often also show decreased plasma tryptophan levels and increased kynurenine concentrations in parallel with elevated concentrations of Th1 type immune activation marker neopterin. In the course of anti-tumor immune response, the pro-inflammatory cytokine interferon gamma (IFN-γ) induces both, the enzyme indoleamine 2,3-dioxygenase (IDO) to degrade tryptophan and the enzyme GTP-cyclohydrolase I to form neopterin.
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