Publications by authors named "Patricia K Luoto"

Background: Longer-term feeding studies suggest that a low-carbohydrate diet increases energy expenditure, consistent with the carbohydrate-insulin model of obesity. However, the validity of methodology utilized in these studies, involving doubly labeled water (DLW), has been questioned.

Objective: The aim of this study was to determine whether dietary energy requirement for weight-loss maintenance is higher on a low- compared with high-carbohydrate diet.

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Objective: To determine the effects of diets varying in carbohydrate to fat ratio on total energy expenditure.

Design: Randomized trial.

Setting: Multicenter collaboration at US two sites, August 2014 to May 2017.

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A research team from Boston Children's Hospital and Harvard Medical School conducted a community-based feeding study in collaboration with Framingham State University (FSU) and Sodexo, the food service contractor at FSU. The study was a randomized controlled trial, implemented on the FSU campus. For the final year of the study, a satellite feeding site was established at Assabet Valley Regional Technical High School.

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Article Synopsis
  • The study investigates the long-term effects of different carbohydrate-to-fat ratios in diets on maintaining weight loss among individuals who are overweight or obese after an initial weight loss period.
  • 164 participants aged 18 to 65 were randomly assigned to one of three controlled diets (high-carb, moderate-carb, low-carb) for 20 weeks, following a standardized weight loss phase.
  • Primary outcomes measured included total energy expenditure and secondary outcomes involved resting energy, physical activity, chronic disease risk, and metabolism-related factors to understand how the diet ratio affected weight maintenance.
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