Publications by authors named "Patricia Islas"
DNA nanotechnology has revolutionized the ability to position matter at the nanoscale, but the preparation of DNA-based architectures remains laborious. To facilitate the formation of custom structures, a fully automated method is reported to produce sequence- and size-defined DNA nanotubes. By programming the sequential addition of desired building blocks, rigid DX-tile-based DNA nanotubes and flexible wireframe DNA structures are attained, where the total number of possible constructs increases as a power function of the number of different units available.
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- DNA nanotubes (NTs) are being researched for their potential in biomedical applications and synthetic biology due to their ability to act as artificial cytoskeletons.
- The study presents a new design of DNA nanotubes with adjustable properties like geometry, cavity size, and length using just four DNA strands and a unique h-motif structure for improved stability and self-assembly.
- These DNA nanotubes can be assembled under physiological conditions and hold promise for uses in biosensors, drug delivery, and other functional materials in future cellular applications.