Comorbid cerebral amyloid angiopathy in dementia and prodromal stages-Prevalence and effects on cognition.

Objectives: To determine the contribution of cerebral amyloid angiopathy to cognitive impairment in MCI and dementia.

Methods: Patients with subjective memory impairment (SMI), amnestic and non-amnestic mild cognitive impairment ((n)aMCI), Alzheimer's disease (AD), mixed and vascular dementia (MD/VD) from our memory clinic were included in this retrospective analysis. Patients underwent neuropsychological testing and cranial magnetic resonance imaging (MRI).

[Coincidence of normal pressure hydrocephalus and Alzheimer`s disease: therapeutic implications and open questions].

Normal pressure hydrocephalus (NPH) is prevalent in aging patient populations. Despite its clinical relevance, many patients with NPH may not receive adequate treatment. Because of the frequency of Alzheimer`s disease in these patients, there could be overlapping pathophysiological mechanisms that are as yet incompletely understood.