Publications by authors named "Patricia Heckmann"

Article Synopsis
  • - The study investigated how the COVID-19 pandemic affected the distribution of systemic anti-cancer therapy (SACT) in Ireland from January 2019 to April 2021, utilizing national pharmacy claims data.
  • - Results showed a significant drop in the dispensing of immunotherapy and targeted therapy post-March 2020, with averages dropping by about 3.3 and 4.1 agents per 100,000 population monthly, indicating healthcare disruptions due to the pandemic.
  • - While the trend for endocrine therapy also slowed significantly after March 2020, no major changes were observed for other types of SACT during the pandemic period.
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Objectives: The use of parenteral systemic anticancer therapy (SACT) has led to improved cancer survival. A quality assurance (QA) system of the aseptic compounding process is necessary to ensure safe and consistent production of parenteral SACT. This scoping review identifies international evidence and practice relating to QA standards in the preparation of parenteral SACT in healthcare establishments.

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Background: Management options for the treatment of melanoma have expanded in recent years. In an era of promising, but expensive novel pharmacological treatments, robust stage-specific melanoma-related cost estimates are necessary to support budgetary planning, evaluation of cost-effectiveness and to contribute to the investment case for prevention.

Methods: A detailed decision model, describing the melanoma care pathway (by disease stage) from diagnosis, through treatment and follow-up was developed over a 5-year time frame from the perspective of the Irish healthcare system.

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