Abnormal transcranial Döppler ultrasonography in children with sickle cell disease.

Background: Stroke is a potentially fatal complication of sickle cell disease in children between 2-16 years and transcranial Döppler has been recommended as a screening method in these cases.

Objective: The main goal of this study was to correlate transcranial Döppler results to complications related to stroke in sickle cell disease and baseline characteristics of the population.

Methods: This was an observational study of children and adolescents with ages between 2-16 years with sickle cell disease who were followed in three centers.

[Evaluation of the fluoride concentration and consumption of mineral water].

Objective: Considering that water is an importance source of fluoride intake, and that the consumption of mineral water and prevalence of dental fluorosis have been increasing, the aim of this study was to evaluate the consumption of mineral water and its fluoride concentration.

Methods: The study was performed in residential districts of the municipality of Bauru, State of São Paulo, by means of stratified sampling via clusters. Each cluster corresponded to one residential block.