Publications by authors named "Patricia F Nunes"
Hematological and Biochemical Characteristics Associated with Cytogenetic Findern Alterations in Adult Patients with Acute Lymphoblastic Leukemia (ALL) from the Northern Region of Brazil.
Biomedicines
November 2024
Acute lymphoblastic leukemia (ALL) is an aggressive neoplasm derived from B and/or T cell lineage (B-ALL; T-ALL). For the first time, this study describes, cytogenetically, the karyotypic alterations in adults with ALL in the northern region of Brazil and their relationship with hematological and biochemical characteristics. Through banding analyses, immunophenotyping, as well as hematological and biochemical examination data obtained directly from patients' records, we found that chromosome 21 aneuploidy was the most frequent.
View Article and Find Full Text PDFHepatitis C and Human Pegivirus Coinfection in Patients with Chronic Hepatitis C from the Brazilian Amazon Region: Prevalence, Genotypes and Clinical Data.
Viruses
September 2023
Article Synopsis
- - The study investigates the prevalence of human pegivirus-1 (HPgV-1) in patients with hepatitis C virus (HCV) in Belém, Brazil, finding that about 28% of HCV-infected individuals are also infected with HPgV-1.
- - Out of 147 participants, 72.1% were solely infected with HCV, while 27.9% were coinfected; HPgV-1 genotypes 1 and 2 were most common among those with HPgV-1.
- - The researchers did not find significant differences in risk factors or the clinical impact of HPgV-1 on HCV, indicating high prevalence but unclear effects on HCV progression,
Hepatitis B and C are the most common causes of liver disease worldwide. The two infections share many similarities such as a global distribution, the same routes of transmission, hepatotropism, and the ability to cause chronic infection. The consequences of HBV/HCV coinfection are still being studied.
View Article and Find Full Text PDFThe Philadelphia (Ph+) chromosome, t(9;22)(q34;q11.2), originates from a chimeric gene called and is present in more than 90% of CML patients. Most patients with CML express the protein p210 and, with a frequency lower than 5%, express rare isoforms, the main one being p190.
View Article and Find Full Text PDFPeople who use crack-cocaine (PWUCC) have numerous vulnerabilities and pose a challenge to health and social assistance services. The exposure to pathogens and risk situations occur differently according to each individual, region and social group. This study identified the presence, genotypes and factors associated with hepatitis E virus (HEV) exposure among a community-recruited cohort of 437 PWUCC in northern Brazil.
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