Cost of adverse drug events related to potentially inappropriate medication use: A systematic review.

Background: The use of potentially inappropriate medications (PIMs) for older people is associated with worse health outcomes owing to the occurrence of adverse drug events (ADEs) and drug interactions, leading to increased health care costs.

Objectives: Identify the costs of ADEs related to PIMs use, in addition to the costs predictors.

Methods: A systematic review was conducted in the PubMed and Scopus databases (until February, 2022), and the report of this study was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.