Publications by authors named "Patricia Courtel"
Major phenolic compounds from olive oil (ArOH-EVOO), oleuropein (Ole), tyrosol (Tyr), and -coumaric acid (-Cou), are known for their antioxidant and neuroprotective properties. We previously demonstrated that their combination could potentiate their antioxidant activity in vitro and in cellulo. To further our knowledge of their electron-transfer properties, Ole, Tyr, and -Cou underwent a spectroelectrochemical study, performed either individually or in equimolar mixtures.
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- Phenolic compounds in olive oil, specifically ArOH-EVOO, have antioxidant and neuroprotective properties but are typically studied in isolation rather than in combination.
- Researchers hypothesized that a mixture of key phenolic compounds—oleuropein, -coumaric acid, and tyrosol (Mix1)—would be more effective than other combinations in reducing oxidative stress in neurons.
- Experimental results showed that Mix1 improved neuronal survival and decreased harmful ROS levels, indicating potential benefits for neurodegenerative diseases like Alzheimer's and Parkinson's.