Publications by authors named "Patricia Correia de Oliveira Saldanha"
Arq Neuropsiquiatr
October 2013
Article Synopsis
- The study investigates early onset multiple sclerosis (MS) in Brazilian patients diagnosed before age 18, highlighting the challenges in diagnosis and management.
- Data was collected retrospectively from 20 MS units across 11 states, resulting in 117 cases, with a mean onset age of 13.7 years and an average disease duration of 10 years.
- Overall, while some cases were severe, most patients with pediatric MS in Brazil exhibited relatively mild symptoms, with low disability levels and an average relapse rate of one episode every 2.5 years.
Arq Neuropsiquiatr
October 2013
Article Synopsis
- Natalizumab is an effective treatment for multiple sclerosis (MS), but there's a risk of developing progressive multifocal leukoencephalopathy (PML) linked to JC virus (JCV) infection.
- A study aimed to determine how common JCV-DNA is among Brazilian MS patients treated with natalizumab, using real-time polymerase chain reaction (PCR) for detection.
- Out of 168 MS patients on natalizumab, 51.2% tested positive for JCV-DNA, contributing valuable data to the global understanding of JCV prevalence in MS patients.
