Effectiveness of a program to improve antibiotic use in children hospitalized in a children's tertiary care facility in Argentina.

Introduction: Inadequate antibiotic use is associated with an increased emergence of resistant microorganisms, higher morbidity and mortality rates, and an impact on public health.

Objective: To assess the effectiveness of a program aimed at improving the use of antimicrobials in patients hospitalized at Hospital Garrahan.

Material And Methods: Prospective, longitudinal, before and after study with no control group.

[Reasons for inappropriate prescribing of antibiotics in a high-complexity pediatric hospital].

Objective: Determine the reasons for inappropriate prescription of antibiotics and identify opportunities to improve prescription of these drugs in pediatric patients hospitalized in intermediate and intensive care units.

Methods: A prospective, descriptive longitudinal study was conducted of pediatric patients in intermediate and intensive care units who received parenteral administration of antibiotics, with the exception of newborns, burn unit patients, and surgical prophylaxis patients. A univariate analysis and multiple logistic regression were performed.