Publications by authors named "Patricia C Liermann"
Article Synopsis
- Tumour necrosis factor (TNF) signaling involves two receptors, TNFR1 and TNFR2, which help balance immune responses in the central nervous system and are relevant in autoimmune diseases like multiple sclerosis.
- Researchers used specially designed mice to test the effects of a drug called ATROSAB that targets TNFR1, finding that it significantly reduced disease severity and immune cell presence in the central nervous system after disease onset.
- The study suggests that anti-TNFR1 therapy could effectively manage autoimmune diseases by limiting immune cell infiltration without changing the overall immune system's structure or function.
