A deterministic approach to the adapted optode placement for illumination of highly scattering tissue.

A novel approach is presented for computing optode placements that are adapted to specific geometries and tissue characteristics, e.g., in optical tomography and photodynamic cancer therapy.

Direct reconstruction of tissue parameters from differential multifrequency EIT in vivo.

The basic purpose of electrical impedance tomography (EIT) is the reconstruction of conductivity distributions. While multifrequency measurements are of common use, the majority of reconstructed images are still conductivity distributions from one single frequency. More interesting than conductivities at each frequency are electrical tissue parameters, which describe the frequency-dependent conductivity changes of tissue.

Solution of the inverse problem of magnetic induction tomography (MIT) with multiple objects: analysis of detectability and statistical properties with respect to the reconstructed conducting region.

Magnetic induction tomography (MIT) is a technique to image the passive electrical properties (i.e. conductivity, permittivity, permeability) of biological tissues.

Reconstruction of the shape of conductivity spectra using differential multi-frequency magnetic induction tomography.

Magnetic induction tomography (MIT) of biological tissue is used for the reconstruction of the complex conductivity distribution kappa inside the object under investigation. It is based on the perturbation of an alternating magnetic field caused by the object and can be used in all applications of electrical impedance tomography (EIT) such as functional lung monitoring and assessment of tissue fluids. In contrast to EIT, MIT does not require electrodes and magnetic fields can also penetrate non-conducting barriers such as the skull.

Fat and hydration monitoring by abdominal bioimpedance analysis: data interpretation by hierarchical electrical modeling.

In a previous publication, it was demonstrated that the abdominal subcutaneous fat layer thickness (SFL) is strongly correlated with the abdominal electrical impedance when measured with a transversal tetrapolar electrode arrangement. This article addresses the following questions: 1) To which extent do different abdominal compartments contribute to the impedance? 2) How does the hydration state of tissues affect the data? 3) Can hydration and fat content be assessed independently? For simulating the measured data a hierarchical electrical model was built. The abdomen was subdivided into three compartments (subcutaneous fat, muscle, mesentery).

Monitoring of lung edema using focused impedance spectroscopy: a feasibility study.

Currently only ionizing or invasive methods are used in clinical applications for the monitoring of extracellular lung water. Alternatively a method called focused conductivity spectroscopy (FCS) is suggested, which aims at reconstructing a pulmonary edema index (PEIX) by measuring the electrical conductivity of the region of interest (ROI) at several frequencies. In contrast to electrical impedance tomography (EIT) a minimum number of strategically placed electrodes is used.

Solution of the inverse problem of magnetic induction tomography (MIT).

Magnetic induction tomography (MIT) of biological tissue is used to reconstruct the changes in the complex conductivity distribution inside an object under investigation. The measurement principle is based on determining the perturbation DeltaB of a primary alternating magnetic field B0, which is coupled from an array of excitation coils to the object under investigation. The corresponding voltages DeltaV and V0 induced in a receiver coil carry the information about the passive electrical properties (i.