Publications by authors named "Patricia Boeti"
Article Synopsis
- The study analyzes outcomes for 844 patients treated for hepatocellular carcinoma (HCC) at a surgery and liver transplantation center, focusing on various curative intent methods such as liver resection (LR), liver transplantation (LT), and radiofrequency ablation (RFA).
- The results show that 73% of the patients had liver cirrhosis, with morbidity rates at 30% and a mortality rate of 4.3%; the overall five-year survival rate was 39%, with LT offering the best outcomes.
- For HCC patients without cirrhosis, LR is preferred, while those with early HCC on cirrhosis benefit most from LT; RFA serves as a potential cure for
In order to analyse whether a C-terminal polybasic sequence represents a nuclear localization signal (NLS) we obtained several truncated and mutant forms of protein of regerating liver (PRL)-3 and evaluated their subcellular localization as compared to the wild-type form. Our results invalidate the hypothesis that this is an NLS. We also analysed the influence of the C- and N-terminal residues on the phosphatase activity of PRL-3.
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