Body composition and resting energy expenditure in clinically stable, non-weight-losing patients with severe emphysema.

Study Objectives: To characterize the metabolic status of weight-stable and clinically stable individuals with advanced emphysema.

Patients: Seventy-nine patients with severe emphysema (FEV(1), 29 +/- 13% of predicted [mean +/- SD]) evaluated for enrollment in the National Emphysema Treatment Trial and 20 age-matched healthy subjects were studied.

Setting: Pulmonary function laboratory of university-affiliated teaching hospital.