An electrochemical/SERS dual-mode immunosensor using TMB/Au nanotag and Au@2D-MoS modified screen-printed electrode for sensitive detection of prostate cancer biomarker.

This study describes a novel dual-mode immunosensor that combines electrochemical (EC) and surface-enhanced Raman scattering (SERS) techniques for the detection of prostate-specific antigen (PSA), a biomarker associated with prostate cancer. The sensor consists of a nanocomposite of gold nanoparticles (AuNPs) deposited on two-dimensional (2D) molybdenum disulfide (Au@MoS) modified on a working carbon electrode of a screen-printed electrode (SPE). Subsequently, the primary antibody (Ab1) is immobilized on the modified electrode, creating Ab1/Au@MoS/SPE for specific recognition of the target PSA.

A toluidine blue/porous organic polymer/2D MoSe nanocomposite as an electrochemical signaling platform for a sensitive label-free aflatoxin B1 bioassay in some crops.

A label-free electrochemical immunosensor using a toluidine blue (TB)/porous organic polymer (POP)/two-dimensional molybdenum diselenide (2D MoSe) nanocomposite is developed for highly sensitive detection of aflatoxin B1 (AFB1) in selected crops. A POP/2D MoSe composite material is employed to modify the surface of a screen-printed carbon electrode (SPCE). Subsequently, TB is adsorbed on the modified SPCE surface, and the resulting TB/POP/2D MoSe composite is then used to construct a biosensor.

A new portable toluidine blue/aptamer complex-on-polyethyleneimine-coated gold nanoparticles-based sensor for label-free electrochemical detection of alpha-fetoprotein.

The quantification of alpha-fetoprotein (AFP) as a potential liver cancer biomarker which is generally found in ultratrace level is of significance in biomedical diagnostics. Therefore, it is challenging to find a strategy to fabricate a highly sensitive electrochemical device towards AFP detection through electrode modification for signal generation and amplification. This work shows the construction of a simple, reliable, highly sensitive, and label-free aptasensor based on polyethyleneimine-coated gold nanoparticles (PEI-AuNPs).

Tunable surface plasmon resonance enhanced fluorescence the stretching of a gold quantum dot-coated aluminum-coated elastomeric grating substrate.

In this study, the surface plasmon resonance (SPR)-enhanced fluorescence properties of gold quantum dots (AuQDs) on an aluminum (Al)-coated polydimethylsiloxane (PDMS) grating substrate were investigated by changing the grating pitch mechanical stretching. The SPR-excitation wavelength of the AuQDs/Al-coated PDMS-grating substrate was tuned by changing the incident light angle from 5° to 60° and stretching it from 0 to 1.0 mm.

Electrochemical detection of matrix metalloproteinase-7 using an immunoassay on a methylene blue/2D MoS/graphene oxide electrode.

Methylene blue (MB) adsorption onto a two-dimensional molybdenum disulfide (2D MoS)/graphene oxide (GO) nanocomposite sitting on a screen-printed carbon electrode (SPCE) is used to develop a new sensitive label-free electrochemical immunosensor for the detection of matrix metalloproteinase-7 (MMP-7) cancer biomarkers. The 2D MoS/GO nanocomposite deposited onto an SPCE provides a large specific surface area, fast electron transfer, and exceptional electrical conductivity. Furthermore, MB adsorbed onto the 2D MoS/GO nanocomposite architecture can be used for signal amplification in electrochemical immunosensors.

The effect of gold quantum dots/grating-coupled surface plasmons in inverted organic solar cells.

We studied the effect of gold quantum dots (AuQDs)/grating-coupled surface plasmon resonance (GC-SPR) in inverted organic solar cells (OSCs). AuQDs are located within a GC-SPR evanescent field in inverted OSCs, indicating an interaction between GC-SPR and AuQDs' quantum effects, subsequently giving rise to improvement in the performance of inverted OSCs. The fabricated solar cell device comprises an ITO/TiO/P3HT : PCBM/PEDOT : PSS : AuQD/silver grating structure.

Fabrication of Miniature Surface Plasmon Resonance Sensor Chips by Using Confined Sessile Drop Technique.

In this study, we demonstrate a simple and efficient method to fabricate miniature surface plasmon resonance (SPR) sensor chips by using confined sessile drop technique. A liquid optical adhesive (NOA 61) was dropped on the circular flat surface of cylindrical substrates made of poly(dimethylsiloxane) (PDMS). The formation of hemispherical optical prisms was accomplished by taking advantage of the sharp edges of cylindrical PDMS substrates that prevented the overflow of liquid NOA 61 at the edge of substrates.