Complete Mitochondrial Genome of (Perciformes: Niphonidae): Genome Characterization and Phylogenetic Analysis.

The species (Cuvier, 1829) is the only representative of the family Niphonidae and the genus , and its taxonomic history is complicated; it is still unclear in a phylogenetic sense. In this study, we report the complete mitochondrial genome of (OP391482), which was determined to be 16,503 bp long with biased A + T contents (53.8%) using next-generation technology.

In vitro regeneration and optimization of physical and chemical mutagenesis protocol in tuberose ( (Medik.) Thiede & Govaerts) cv. 'Arka Vaibhav'.

Purpose: Tuberose ( [Medik.]) is a vegetatively propagated commercial flower crop with limited genetic variability. Crossing barriers prevailing in tuberose necessitates modern breeding techniques like in vitro mutagenesis to generate variability.

Role of Injectable Platelet-Rich Fibrin in the Management of Soft and Hard Tissue Periodontal Regeneration in Dentistry: Protocol for a Systematic Review.

Background: Injectable platelet-rich fibrin (i-PRF) has the capacity to release great amounts of several growth factors, as well as to stimulate increased fibroblast migration and the expression of collagen, transforming growth factor β, and platelet-derived growth factor. Consequently, i-PRF can be used as a bioactive agent to promote periodontal tissue regeneration.

Objective: We aim to compare and evaluate the effectiveness of i-PRF in periodontal tissue regeneration.

Neuroendocrine tumour of the urinary bladder.

We report a rare case of urinary bladder neuroendocrine tumour (NET) in a young, non-smoking man. He had no known risk factors and no comorbidities. After being diagnosed with a bladder tumour while being investigated for flank pain and poor renal function, he was treated with transurethral resection of the bladder tumour and deroofing of ureters bilaterally.

Neurocysticercosis: unwinding the radiological conundrum.

Purpose: To study the distinct imaging characteristics of parenchymal neurocysticercosis (NCC) that aid in distinguishing it from other diseases.

Material And Methods: Two hundred fifty patients with NCC were selected based on identification of the scolex. T2 weighted, T1 fluid attenuated inversion recovery (FLAIR), T2 FLAIR, susceptibility weighted imaging, constructive interference in steady state, diffusion weighted imaging, and T1 weighted contrast sequences were performed.

Assessing ADHD prevalence and comorbidities in the United States: Insights from the Substance Abuse and Mental Health Services (SAMHSA) data.

This study analyzes 2022 data from SAMHSA's Mental Health Client-Level Data (MH-CLD) to investigate ADHD prevalence and comorbidity. The findings reveal that 10.70% of the 5,899,698 patients were diagnosed with ADHD, indicating a high demand for targeted resources.

Effect of low-level laser therapy on proliferation and cytotoxicity of mouse fibroblasts and human fibroblasts: An study.

Background: Diode laser is known for its biostimulatory effects on various cell populations such as osteoblasts and fibroblasts. The usage of low-level laser therapy for photobiomodulation depends on its type, emission wavelength, and energy selected. Previously performed studies have determined its effect on cell proliferation and cytotoxicity; however, the results were inconsistent.

Impact of Hypothyroidism in Pregnancy on Feto-Maternal Outcomes: A Prospective Observational Study.

Introduction Hypothyroidism represents an endocrine disorder marked by the insufficient production of hormones by the thyroid gland, with significant effects on bodily functions. Its occurrence during pregnancy is of particular concern due to its profound effects on both maternal and fetal health outcomes. Aim To study the impact of hypothyroidism in pregnancy and its correlation with feto-maternal outcomes.

CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry.

Spectral flow cytometry provides greater insights into cellular heterogeneity by simultaneous measurement of up to 50 markers. However, analyzing such high-dimensional (HD) data is complex through traditional manual gating strategy. To address this gap, we developed CAFE as an open-source Python-based web application with a graphical user interface.

Comprehensive Assessment of Cannabidiol and HU308 in Acute and Chronic Colitis Models: Efficacy, Safety, and Mechanistic Innovations.

Cannabinoids are emerging as promising treatments for inflammatory diseases such as ulcerative colitis. Specifically, cannabinoid 2 (CB2) receptors, which are upregulated during inflammation, have been distinctively linked to anti-inflammatory and analgesic effects. HU308, a synthetic cannabinoid developed to activate CB2 receptors selectively, aims to minimize unwanted off-target side effects.

Approach to determining etiology of hypophosphatemia in a patient with coexisting phosphaturic mesenchymal tumor and fibrous dysplasia.

Dysregulated FGF23 production is a demonstrated cause of hypophosphatemia and osteomalacia. Diseases associated with these conditions include phosphaturic mesenchymal tumor (PMT) causing tumor induced osteomalacia, various forms of rickets, and fibrous dysplasia (FD). Coexistence of 2 conditions that can increase FGF23 concentrations is rare.

Role of artificial intelligence in cancer detection using protein p53: A Review.

Normal cell development and prevention of tumor formation rely on the tumor-suppressor protein p53. This crucial protein is produced from the Tp53 gene, which encodes the p53 protein. The p53 protein plays a vital role in regulating cell growth, DNA repair, and apoptosis (programmed cell death), thereby maintaining the integrity of the genome and preventing the formation of tumors.

A Castration-Resistant Prostate Tumor With Unusual Anatomy Treated Using Daily Online Adaptive Radiotherapy.

Daily online adaptive radiotherapy (OART) is useful in radiotherapy of prostate cancer to reduce doses to the rectum and bladder which pose a challenge because of daily variation in shape and size. It also helps to reduce target margins while still maintaining target coverage. We present a case of prostate cancer resistant to androgen deprivation therapy and systemic therapy which was difficult to treat with definitive radiotherapy because of the unusual anatomical shape of the tumor impinging into the rectum.

Castleman's Disease Presenting as an Unusual Pelvic Retroperitoneal Mass.

Castleman's disease (CD) is characterised by benign lymphoepithelial proliferation and is a peculiar form of angiofollicular lymph node hyperplasia rather than a neoplasm or a hamartoma. CD is broadly classified as unicentric CD (UCD) and multicentric CD. In the unicentric variant, patients have localised disease affecting only a single lymph node or a group of adjacent nodes in a single region, which clinically presents as an enlarging mass without any other significant symptoms.

Sociodemographic and Psychological Factors Influencing Human Milk Donation: A Cross-Sectional Study of 420 Lactating Mothers in Vijayapura.

Background Breastfeeding is crucial for infant health, but not all mothers can breastfeed due to various constraints. Making human milk banks (HMBs) is essential for providing donor milk to preterm and sick infants. Methods  This is a cross-sectional study at Shri BM Patil Medical College Hospital and Research Centre in Vijayapura involving 420 lactating mothers.

EDSSR: a secure and power-aware opportunistic routing scheme for WSNs.

Motivated by the pivotal role of routing in Wireless Sensor Networks (WSNs) and the prevalent security vulnerabilities arising from existing protocols, this research tackles the inherent challenges of securing WSNs. Many current WSN routing protocols prioritize computational efficiency but lack robust security measures, making them susceptible to exploitation by malicious actors. The prevalence of reactive protocols, chosen for their lower bandwidth consumption, exacerbates security concerns, as proactive alternatives require more resources for maintaining network routes.

Role of Serum Magnesium on Insulin Resistance in Overweight and Obese Children.

Background Childhood obesity has become a global epidemic, with projections indicating it could affect 25% of children under 16 by 2050. This rise poses significant health risks, including early onset of type 2 diabetes and cardiovascular diseases. Recent research has shown a correlation between insulin action and magnesium levels, highlighting the link between low serum magnesium levels and obesity.

Enteral Nutrition in Neonates on Inotropic Support Admitted to a Tertiary Neonatal Intensive Care Unit: A Prospective Cohort Study.

Background Early initiation of enteral feeding in neonates on inotropic support may improve clinical outcomes compared to intravenous fluids, but the safety and optimal inotrope levels for enteral nutrition remain unclear. This study aims to assess the early initiation of enteral feeding versus intravenous fluids in newborns on inotrope support and to compare the clinical outcome in terms of hospital stay, morbidity, and mortality in neonates with enteral feed versus intravenous (IV) fluid group on inotropes. It also focuses on evaluating the safety of enteral nutrition in neonates with inotropic support and determining the cutoff levels of the inotropes at which enteral feed is well tolerated.