Publications by authors named "Patience N Obiagwu"

Article Synopsis
  • - The P-Process offers a structured, five-step framework for improving vaccination strategies by focusing on social and behavioral factors, integrating with health systems, and collaborating with local experts to effectively address public health challenges.
  • - A multi-faceted communication intervention was created in India and Nigeria to boost vaccine uptake among hospitalized children, involving interviews with caregivers, co-development workshops, and piloting of materials with various stakeholders.
  • - Following the P-Process, feedback from caregivers and healthcare workers indicated that their communication improved, and caregivers felt their concerns about vaccination were addressed, demonstrating a successful approach to enhancing vaccine uptake.
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Article Synopsis
  • Glomerulonephritis (GN) is a major cause of kidney failure in Africa, with different types having varying prevalence based on location and genetic factors.
  • Researchers conducted a study analyzing biopsy-proven primary GNs from 2010 to 2022 across 8 African countries, finding a total of 6,494 individuals affected.
  • The most common histologic subtypes were focal segmental glomerulosclerosis (FSGS) at 26.10% and minimal change disease (MCD) at 22.40%, highlighting the need for improved diagnosis and treatment protocols in different age groups and regions.
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Background: Prediabetes and diabetes are important metabolic public health problems, especially among adolescents. However, they are being given little or no attention, especially in Sub-Saharan Africa (SSA). Prediabetes increases the risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular diseases.

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Introduction: Derangement in serum electrolytes and kidney function is often overlooked, especially in resource-constrained settings, and associated with increased risk of morbidity and mortality. This study aimed to describe the burden of derangements in serum electrolytes and kidney function in children presenting to a tertiary hospital in Nigeria.

Methods: The laboratory records of all children who had serum electrolytes urea and creatinine ordered on their first presentation to hospital between January 1 and June 30, 2017 were retrospectively reviewed.

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Juvenile Dermatomyositis is a rare idiopathic autoimmune and inflammatory myopathy and vasculopathy whose hallmarks are symmetrical proximal muscle weaknesses and a characteristic rash. Only few cases have been reported in West Africa subregion. We present a 14-year old Nigerian girl with clinical and histopathologic features of definitive juvenile dermatomyositis based on EULAR/ACR classification criteria but probable Juvenile dermatomyositis according to Bohan and Peter criteria.

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Background: Human immunodeficiency virus (HIV) infection has significant effects on child development. We report the outcome of gross motor developmental assessment in HIV-infected children <2 years compared with that of uninfected children.

Materials And Methods: Every child <2 years of age presenting for the first time to the pediatric outpatient department of the hospital over 3 months was studied.

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Background: Elevated mean pulmonary artery pressure (mPAP) and right heart failure increase mortality in patients with chronic kidney disease (CKD).

Objectives: The objective of this study is to determine the prevalence of elevated mPAP in children with CKD compared with matched controls and to ascertain the relationship between elevated mPAP with right ventricular dysfunction and history of hemodialysis.

Materials And Methods: A cross-sectional comparative study of mPAP and tricuspid annular plane systolic excursion of 21 children with CKD and age- and sex-matched controls asymptomatic for cardiac disease was conducted.

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Background: Renal artery revascularisation procedures are usually carried out on children with renal artery stenosis from varied causes, including Takayasu's arteritis. Reports on the outcome of such procedures in children usually refer to the improvement in blood pressure, with only minimal mention of effects on renal function.

Objective: Salvageability of renal function in children who underwent renal revascularisation for Takayasu's arteritis-induced renal artery stenosis (TARAS) was the focus of this study.

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Objective: To determine the cost of the dialytic management of paediatric acute kidney injury in a low-income country.

Methods: All children under the age of 15 years, who had either peritoneal dialysis or haemodialysis for acute kidney injury in Aminu Kano Teaching Hospital over a 1-year period, were studied. The average cost of each dialysis modality was estimated.

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Background: The safety of percutaneous renal biopsy (PRB) has been debated. The primary aim of this study was to review the procedure and secondary aim is to evaluate the safety of PRB in children in a developing nephrology unit in Northern Nigeria.

Methods: Renal biopsies carried out in the renal unit of a teaching hospital in northern Nigeria between November 2011 and April 2013 were retrospectively reviewed.

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