Microplastic pollution: A global perspective in surface waters, microbial degradation, and corresponding mechanism.

Plastics are incredibly useful materials that have many benefits for both society and individual daily lives. However, the extensive utilization of plastic and plastic-derived products has led to plastic pollution in various environmental compartments across the world at alarming levels. Due to different biogeochemical processes, this plastic waste is broken down into tiny, omnipresent, and long-lasting fragments known as microplastics (<5 mm), which are causing great concern among scientists.

Incidence and Prognostic Significance of Arrhythmia in Acute Myocardial Infarction Presentation: An Observational Study.

Background Arrhythmias are well-recognized complications of acute myocardial infarction (AMI) and are an important risk factor for mortality in both men and women across a wide age range. Aim This study aims to analyze the incidence of arrhythmia in patients with AMI with respect to age, gender distribution, and location of AMI and also to evaluate the prognostic factors of mortality in patients with AMI. Methods This prospective, observational, and cross-sectional study included 300 patients admitted within an hour of the presentation of AMI at a Super Speciality Hospital, MGMMC (Mahatma Gandhi Memorial Medical College), Indore, after fulfilling the inclusion criteria.

Total extra-peritoneal approach to radical cystectomy with ureterostomy: A novel technique for the elderly and frail.

Objectives: Radical cystectomy with urinary diversion is the gold standard treatment for bladder cancer (high-risk/muscle invasive). The transperitoneal approach is associated with significant gastrointestinal complications like ileus. In the elderly and frail with a single functional kidney, we describe an extraperitoneal technique of radical cystectomy, with a ureterostomy, to be performed without general anesthesia.

Cardio-Oncology's Modern Approaches to Prevent Doxorubicin-Induced Cardiotoxicity: A Systematic Review.

Advances in the field of oncology have led to the advent of doxorubicin (DOX), an anthracycline chemotherapeutic agent, through which cancer survival rates have remarkably improved. There has, however, been a rise in adverse effects from the use of DOX, most notably cardiotoxicity. DOX-induced cardiotoxicity is thought to arise through the generation of reactive oxygen species (ROS), causing mitochondrial dysfunction in the cardiomyocytes.

Correlation of Clinical Parameters with Findings of High-resolution Computed Tomography Chest in COVID-19 Patients.

: Studies have shown that high-resolution computed tomography (HRCT) of the chest along with clinical parameters is useful in determining the clinical progression, extent of disease and severity of illness in patients with COVID-19. Hence, the present study was done to assess HRCT chest features in patients with COVID-19 infection and to find its association with clinical status in these cases. : This was an observational study over the period of 18 months in patients diagnosed with COVID-19 disease following reverse transcription polymerase chain reaction (RT-PCR).

Identifying patterns of pain, depression, anxiety, interpersonal trauma exposure, and nonmedical prescription opioid use: Latent class analysis among patients with chronic pain.

Background: Chronic pain in the context of certain factors may be associated with potential for nonmedical prescription opioid use; however, identifying this risk can be challenging and complex. Several variables alone have been associated with non-prescribed opioid use, including depression, anxiety, pain interference, and trauma exposure. Prior research has often failed to integrate these assessments together, which is important as these factors may cluster together in important and complex ways.

Artificial Intelligence Assisted Multi-modal Photoacoustic-Ultrasound Imaging for Studying Renal Tissue Function and Hemodynamics.

Combined functional-anatomic imaging modalities, which integrate the benefits of visualizing gross anatomy along with the functional or metabolic information of tissue has revolutionized the world of medical imaging. However, such existing imaging modalities are very costly. An alternative option could be a hybrid modality combining contrast-enhanced ultrasound, doppler and photoacoustic imaging.

A comparative evaluation of the effect of alcoholic and non alcoholic beverages on tooth enamel surface pretreated with β-tricalcium phosphate, bioactive glass and amine fluoride: an study.

Background And Aims: The aim of this study is to quantitatively evaluate the effect of different alcoholic and non alcoholic beverages on the tooth enamel surface topography pretreated with various remineralizing agents using Atomic Force Microscopy.

Methods: 120 tooth specimens were prepared from 60 freshly extracted intact human premolars by sectioning from mesial to distal surfaces using low speed diamond discs and were randomly assigned to study groups and control group. Specimens of Group I, Group II and Group III were pre-treated with β-Tri calcium phosphate, bioactive glass and amine fluoride respectively for 4 minutes for 28 days, followed by storage in artificial saliva.

Sarcomatoid Carcinoma Metastasis to the Colon from a Small Renal Mass: Case Report with Review of Literature.

A third of patients with renal cell carcinoma (RCC) present with metastatic disease. Metastasis in RCC from small renal mass (SRM) (≤4 cm) is rare. We report a case of stage cT1a clear-cell RCC with low-risk features on pathology presenting with disproportionately large synchronous solitary metastasis to the transverse colon.

A scalogram tensor decomposition based ECG quality assessment.

ECG quality assessment is crucial for reducing false alarms and physician strain in automated diagnosis of cardiovascular diseases. Recent researches have focused on constructing an automatic noisy ECG record rejection mechanism. This work develops a noisy ECG record rejection system using scalogram and Tucker tensor decomposition.

Exploring the Impact of Book Club Participation on Clinicians' Empathy and Reflection on Empathetic Practice: A Wake-Up Call.

Introduction:  Empathy is associated with desirable outcomes in healthcare, including improved patient-clinician rapport, fewer patient complications, and reduced clinician burnout. Despite these benefits, research suggests empathy declines during professional training. This study aimed to explore the impact of book club participation on clinicians' and trainees' empathy and perspectives on empathetic patient care.

Identification of Common Dysregulated Genes in COVID-19 and Hypersensitivity Pneumonitis: A Systems Biology and Machine Learning Approach.

A comprehensive knowledge on systems biology of severe acute respiratory syndrome coronavirus 2 is crucial for differential diagnosis of COVID-19. Interestingly, the radiological and pathological features of COVID-19 mimic that of hypersensitivity pneumonitis (HP), another pulmonary fibrotic phenotype. This motivated us to explore the overlapping pathophysiology of COVID-19 and HP, if any, and using a systems biology approach.

Conditional survival in patients treated for gastric cancer with a curative intent.

Background And Objectives: Conditional survival (CS) provides the probability that a patient who has already survived a certain number of years after treatment will survive an additional number of years. We aim to study the CS of patients with gastric cancer.

Methods: Patients who underwent curative intent treatment for gastric cancer in a single institution between 2007 and 2018 were included in the analysis.

Application of Fourier-Bessel expansion and LSTM on multi-lead ECG for cardiac abnormalities identification.

. The availability of online electrocardiogram (ECG) repositories can aid researchers in developing automated cardiac abnormality diagnostic systems. Using such ECG repositories, this study aims to develop an algorithm that can assist physicians in diagnosing cardiac abnormalities.

Spatial Relationship of Maxillary Posterior Teeth with Maxillary Sinus Floor in Sagittal, Coronal and Axial Planes by Using Cone-Beam Computed Tomography in a Subpopulation of Central India.

Inadvertent perforation of the root apex during endodontic procedure in maxillary posterior teeth may unnecessarily invite the complications of sinusitis or inflammatory responses. This becomes even more important when performing endodontic surgical procedures. Thus, it is mandatory to have the precise knowledge of anatomic structures which are in close proximity to the apex of roots and its variations among different geographic area.

Evaluation of titanium mesh and fibers in reinforcing endodontically treated molars: An study.

Aim/objective: We aimed to evaluate the fracture resistance of titanium mesh and fibers that could aid as a substitute for crown coverage.

Materials And Methodology: Forty extracted human mandibular molar teeth were selected for this study and were divided into four groups ( = 10). Access cavity preparation was done in all experimental teeth (Groups 2-4) maintaining 1.

Automated diagnosis of coronary artery disease using scalogram-based tensor decomposition with heart rate signals.

Early identification of coronary artery disease (CAD) can facilitate timely clinical intervention and save lives. This study aims to develop a machine learning framework that uses tensor analysis on heart rate (HR) signals to automate the CAD detection task. A third-order tensor representing a time-frequency relationship is constructed by fusing scalograms as vertical slices of the tensor.

A Comparative Evaluation of Sealing Ability of Five Different Materials for Furcation Perforation Repair Using UV-Spectrophotometric Analysis: An In-Vitro Study.

This in-vitro study was done to compare the sealing ability of Mineral trioxide aggregate (MTA), Biodentine, a mixture of MTA and Glass ionomer cement (GIC) in 2:1 and 1:1 ratio and MTA CEM, as furcation repair material using a dye extraction leakage model in the department of Conservative Dentistry and Endodontics from January 2020 to December 2020. Eighty five extracted molars with divergent and well formed roots were selected for study and were randomly divided according to the material used for perforation repair. Group A: MTA, Group B: Biodentine, Group C: MTA mixed with GIC in 2:1 ratio.

Impacts of Cognitive Behavioral Therapy for Insomnia and Pain on Sleep in Women with Gynecologic Malignancies: A Randomized Controlled Trial.

Insomnia is an adverse cancer outcome impacting mood, pain, quality of life, and mortality in cancer patients. Cognitive Behavioral Therapy (CBT) is an evidence-based treatment for diverse psychophysiological disorders, including pain and insomnia. Primarily studied in breast cancer, there is limited research on CBT within gynecology oncology.

Tensor learning of pointwise mutual information from EHR data for early prediction of sepsis.

Early detection of sepsis can facilitate early clinical intervention with effective treatment and may reduce sepsis mortality rates. In view of this, machine learning-based automated diagnosis of sepsis using easily recordable physiological data can be more promising as compared to the gold standard rule-based clinical criteria in current practice. This study aims to develop such a machine learning framework that demonstrates the quantification of heterogeneity within the tabular electronic health records (EHR) data of clinical covariates to capture both linear relationships and nonlinear correlation for the early prediction of sepsis.

Review of biomarker systems as an alternative for early diagnosis of ovarian carcinoma.

Early diagnosis of ovarian carcinoma is bound to boost the long-term endurance rate of the patients. Most ovarian tumors happen post menopause when the ovaries have no vital operation and therefore irregular ovarian role causes no signs. According to Muinao T.

Percutaneous Tracheostomy in COVID-19 Patients: A Four-step Safe Protocol.

Background: Coronavirus disease-2019 (COVID-19) pandemic has inundated healthcare systems globally especially resources in intensive care units (ICUs). Tracheostomy may be required in critically ill COVID-19 patients to facilitate weaning and to optimize resources like ventilator and ICU beds. Percutaneous tracheostomy (PCT) has become the standard of care globally in ICUs; however, it is considered a high-risk procedure in COVID-19 patients because of the inherent risk of aerosol generation.

Tocilizumab Use in COVID-19 Cytokine-release Syndrome: Retrospective Study of Two Centers.

Introduction: Cytokine-release syndrome (CRS) in COVID-19 patients can cause multiorgan failure and higher mortality. We used a structured protocol based on clinical, biochemical, and interleukin 6 (IL-6) criteria for the identification of the subset of patients with CRS and analyzed the use of tocilizumab for their treatment.

Materials And Methods: We did a retrospective case-control analysis of all COVID-19 patients between 15 March and 15 May 2020 with severe to critical disease in ICU.