Biotic and abiotic stress affects the stability of housekeeping genes in Catla Labeo catla.

Objective: The choice of a stable reference gene plays a crucial role in gene expression analysis. In most cases, the choice of housekeeping gene (HKG) is quite random. However, the expression of HKGs varies under different experimental conditions and in different tissues.

Elevated Perspectives: Unraveling Cardiovascular Dynamics in High-Altitude Realms.

High-altitude regions pose distinctive challenges for cardiovascular health because of decreased oxygen levels, reduced barometric pressure, and colder temperatures. Approximately 82 million people live above 2400 meters, while over 100 million people visit these heights annually. Individuals ascending rapidly or those with pre-existing cardiovascular conditions are particularly vulnerable to altitude-related illnesses, including Acute Mountain Sickness (AMS) and Chronic Mountain Sickness (CMS).

Initiation or switch to insulin degludec/insulin aspart in adults with type 2 diabetes in India: Results from a prospective, non-interventional, real-world study.

Aim: To investigate clinical outcomes in adults with type 2 diabetes (T2D) after insulin degludec/insulin aspart (IDegAsp) treatment in a real-world setting.

Methods: The 26 weeks study involved 1102 adults with T2D who were either initiated with or switched to IDegAsp according to local practice in six countries. It was an open-label, non-interventional study.

Role of Nonalcoholic Fatty Liver Disease in Periodontitis: A Bidirectional Relationship.

Nonalcoholic fatty liver disease (NAFLD) and periodontitis share common risk factors such as obesity, insulin resistance (IR), and dyslipidemia, which contribute to systemic inflammation. It has been suggested that a bidirectional relationship exists between NAFLD and periodontitis, indicating that one condition may exacerbate the other. NAFLD is characterized by excessive fat deposition in the liver and is associated with low-grade chronic inflammation.

Retrospective Study of Diabetic Retinopathy and Macular Edema in Southern Part of Bangladesh.

Background: Diabetic mellitus is a vision-threatening disease because it causes diabetic retinopathy worldwide. The main focus of this research is to determine the prevalence and assess the visual outcome in diabetic retinopathy and macular edema patients by injecting Bevacizumab clinically.

Methods: This hospital-based trial case was conducted in Khulna BNSB Eye Hospital, Bangladesh.

Evaluation of uncertainty in personal dose measured using CaSO4:Dy-based TLD badge at different workplaces.

The metrological quality of a measurement is characterised by evaluating the uncertainty in the measurement. In this paper, uncertainty in personal dose measured using individual monitoring CaSO4:Dy-based thermoluminescence dosimeter badge is evaluated by application of the guide to the expression of uncertainty in measurement method. The present dose reporting quantity, whole body dose (WBD) and the proposed quantity, personal dose equivalent, Hp(10) has been used as measurands.

Indigo dyes: Toxicity, teratogenicity, and genotoxicity studies in zebrafish embryos.

Wastewater released by textile dyeing industries is a major source of pollution. Untreated wastewater released from indigo dyeing operations affects aquatic ecosystems and threatens their biodiversity. We have assessed the toxicity of natural and synthetic indigo dye in zebrafish embryos, using the endpoints of teratogenicity, genotoxicity, and histopathology.

An India soyabean dataset for identification and classification of diseases using computer-vision algorithms.

Intelligent agriculture heavily relies on the science of agricultural disease image recognition. India is also responsible for large production of French beans, accounting for 37.25% of total production.

4mC-CGRU: Identification of N4-Methylcytosine (4mC) sites using convolution gated recurrent unit in Rosaceae genome.

An epigenetic modification is DNA N4-methylcytosine (4mC) that affects several biological functions without altering the DNA nucleotides, including DNA conformation, cell development, replication, stability, and DNA structural changes. To prevent restriction enzyme from damaging self-DNA, 4mC performs a critical role in restriction-modification functions. Existing studies mainly focused on finding hand-crafted features to identify 4mC locations, but these methods are inefficient due to high time consuming and high costs.

Isolation and Characterization of Cow-, Buffalo-, Sheep- and Goat-Milk-Derived Extracellular Vesicles.

Milk is a complex biological fluid that has high-quality proteins including growth factors and also contains extracellular vesicles (EVs). EVs are a lipid bilayer containing vesicles that contain proteins, metabolites and nucleic acids. Several studies have proposed that EVs in cow milk can survive the gut and can illicit cross-species communication in the consuming host organism.

On the dynamic reconfigurable implementations of MISTY1 and KASUMI block ciphers.

Novel hardware architectures for dynamic reconfigurable implementation of 64-bit MISTY1 and KASUMI block ciphers are proposed to enhance the performance of cryptographic chips for secure IoT applications. The SRL32 primitive (Reconfigurable Look up Tables-RLUTs) and DPR (Dynamic Partial Reconfiguration) are employed to reconfigure single round MISTY1 / KASUMI algorithms on the run-time. The RLUT based architecture attains dynamic logic functionality without extra hardware resources by internally modifying the LUT contents.

Assessment of toxicity potential of neglected Mithi River water from Mumbai megacity, India, in zebrafish using embryotoxicity, teratogenicity, and genotoxicity biomarkers.

The Mithi River begins at Vihar Lake and flows through the industrial hub of the city of Mumbai, India, and merges with the Arabian Sea at Mahim Creek. The current study was carried out to assess the ecotoxicological effects of the Mithi River surface water in zebrafish (Danio rerio) embryos. Water samples were collected from ten sampling sites (S1 to S10) located along the course of the Mithi River.

A machine learning approach for correcting glow curve anomalies in CaSO:Dy-based TLD dosimeters used in personnel monitoring.

The study presents a novel approach to analysing the thermoluminescence (TL) glow curves (GCs) of CaSO:Dy-based personnel monitoring dosimeters using machine learning (ML). This study demonstrates the qualitative and quantitative impact of different types of anomalies on the TL signal and trains ML algorithms to estimate correction factors (CFs) to account for these anomalies. The results show a good degree of agreement between the predicted and actual CFs, with a coefficient of determination greater than 0.

Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells.

Cancer cachexia is a wasting syndrome characterised by the loss of fat and/or muscle mass in advanced cancer patients. It has been well-established that cancer cells themselves can induce cachexia via the release of several pro-cachectic and pro-inflammatory factors. However, it is unclear how this process is regulated and the key cachexins that are involved.

Tuning the electrophoretic separations on a surface-accessible and flexible fibre-based microfluidic devices.

Electrophoresis on textile fiber substrates provides a unique surface-accessible platform for the movement, separation and concentration of charged analytes. The method employs the inherently inbuilt capillary channels existing within textile structures, which can support electroosmotic and electrophoretic transport processes upon applying an electric field. Unlike confined microchannels in classical chip-based electrofluidic devices, the capillaries formed by the roughly oriented fibers within textile substrates can impact the reproducibility of the separation process.

A Novel Low-Cost Compact High-Performance Flower-Shaped Radiator Design for Modern Smartphone Applications.

This manuscript examines the design principle and real-world validation of a new miniaturized high-performance flower-shaped radiator (FSR). The antenna prototype consists of an ultracompact square metallic patch of 0.116λ × 0.

Monte Carlo Study on Dose Distributions Around Ir, Yb, and I Brachytherapy Sources Using EGSnrc-based egs_brachy User-code.

Introduction: As per the recommendations of the American Association of Physicists in Medicine Task Group 43, Monte Carlo (MC) investigators should reproduce previously published dose distributions whenever new features of the code are explored. The purpose of the present study is to benchmark the TG-43 dosimetric parameters calculated using the new MC user-code egs_brachy of EGSnrc code system for three different radionuclides Ir, Yb, and I which represent high-, intermediate-, and low-energy sources, respectively.

Materials And Methods: Brachytherapy sources investigated in this study are high-dose rate (HDR) Ir VariSource (Model VS2000), Yb HDR (Model 4140), and I -low-dose-rate (LDR) (Model OcuProsta).

Economic Burden of Severe Hypoglycemia Among Patients With Diabetes Mellitus.

Background: Bangladesh is anticipated to have the eighth-highest number of diabetic patients within the next 15 years. Approximately one-fifth of adult diabetes patients reside in Southeast Asian nations. This study aimed to find out the economic burden of extreme hypoglycemia on diabetic sufferers in Bangladesh.

Efficacy and Safety of Empagliflozin in Patients with Type 2 Diabetes Mellitus Fasting During Ramadan: A Real-World Study from Bangladesh.

Aim: In Bangladesh, there is a large population of Muslims with type 2 diabetes mellitus (T2DM) who fast during Ramadan. Changes in the pattern of meal and fluid intake during this long-fasting hours may increase the risk of hypoglycaemia, hyperglycaemia, and dehydration. Our key point of focus was to evaluate the efficacy and safety of Empagliflozin, a sodium-glucose co transporter 2 inhibitor (SGLT2i), in patients with T2DM while fasting during Ramadan.

The soft tissue esthetic outcome with and without immediate provisionalization in immediate implants: A systematic review and meta-analysis.

Aim: This systematic review and meta-analysis aimed at checking influences of immediate provisionalization on the primary esthetic outcome by Pink Esthetic Score (PES) as well as other secondary soft tissue outcomes such as bleeding on probing, probing depth, plaque index, mesial papillary recession, distal papillary recession, and midfacial mucosal recession of the peri-implant mucosa around immediately placed implants in the anterior maxilla.

Setting And Design: This systematic review and meta-analysis was evaluated using the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines.

Materials And Methods: The relevant studies were found in the databases such as MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials, Science Direct, and Google Scholar.

Significance of and e on the Growth Performance, Haematological Traits, Serum Biochemistry, Faecal and Caeca Microbiota of Broiler Chickens.

Objective: The aim of the study was to supplement and yeast in broiler feed by replacing immunomodulators to develop antibiotic free meat and egg production by analyzing broiler performance, haematological traits, serum biochemistry, histopathology, fecal bacterial count, and metagenomic analysis of broiler ceca.

Method: Two cultures i.e.

Understanding the Effect of an Amorphous Surface on the Ultrafast Dynamics of a Heterogeneous Photoinduced Reaction: CDI Photoinduced Reaction on Amorphous Cerium Oxide Films.

In this work, to understand how an amorphous surface influences the dynamics of surface photoinduced reactions, pump-probe spectroscopy in conjunction with mass spectrometry is employed to track the ultrafast evolution of intermediates and final products with time, mass, and energy resolution. As a model system, the photoinduced reaction of CDI adsorbed on amorphous cerium oxide films is investigated. A fraction of the first intermediates produced on a freshly prepared surface is trapped to passivate the surface.