Frenolicins H and I from the caterpillar-associated sp. TBRC17107.

Two undescribed frenolicins H and I ( and ) along with six previously described frenolicin analogues [frenolicins A (), B (), UCF76-B (), E - G ( - )] and two anthraquinones [3,8-dihydroxy-1-propylanthraquinone-2-carboxylic acid () and 3,8-dihydroxy-1-propylanthraquinone ()] were isolated from a longkong bark eating caterpillar-derived sp. TBRC17107. The chemical structures were determined by NMR spectroscopic information and HRESIMS data.

Cytotoxic cytochalasans from cultures of the fungus TBRC-BCC 79240.

Fourteen new cytochalasans, brunnesins A-N (1-14), along with eleven known compounds, were isolated from the culture extracts of the insect pathogenic fungus strain TBRC-BCC 79240. The compound structures were established by spectroscopy, X-ray diffraction analysis, and electronic circular dichroism. Compound 4 exhibited antiproliferative activity against all cell lines tested (mammalian), with 50% inhibition concentration (IC) values ranging from 2.

Abyssomicin derivatives from the rhizosphere soil actinomycete Microbispora rhizosphaerae sp. nov. TBRC6028.

Three undescribed abyssomicin derivatives, including microbimisin, abyssomicins Z1, and Z2, were isolated from the soil actinomycete Microbispora rhizosphaerae sp. nov. TBRC6028.

Antibacterial, antitubercular, antimalarial and cytotoxic substances from the endophytic Streptomyces sp. TBRC7642.

Eight previously undescribed naturally-occurring compounds, including abyssomycins Y - Z, methyl aeruginoate, desferri-ferrithocin-4-hydroxyphenethylester, streptomethiocins A - B, furaquinocin I, and streptolactone, along with eleven known compounds were isolated from the endophytic Streptomyces sp. TBRC7642. The chemical structures were determined based on spectroscopic means including 1D, 2D NMR spectroscopy and mass spectrometry.

Secondary metabolites from cultures of the ant pathogenic fungus BCC 2728.

Five new compounds, iranginins A-E (-), together with sixteen known compounds were isolated from the insect pathogenic fungus BCC 2728. The structures and the absolute configurations of the new compounds were established by spectroscopic analyses, the application of modified Mosher's method (for ), ECD calculation (for ), and X-ray crystallographic analysis (for ). LL-Z1640-5 and mucorisocoumarin C were active against (MIC 41.

The potential of a fluorescent-based approach for bioassay of antifungal agents against chili anthracnose disease in Thailand.

Severe chili anthracnose disease in Thailand is caused by Colletotrichum gloeosporioides and C. capsici. To discover anti-anthracnose substances we developed an efficient dual-fluorescent labeling bioassay based on a microdilution approach.

Ring B aromatic norpimarane glucoside from a Xylaria sp.

A novel 20-norpimarane glucoside, xylopimarane (1), together with the known sphaeropsidin C (2) and clonostachydiol (3), was isolated from the fungus Xylaria sp. BCC 4297. Compound 1 exhibited cytotoxicity to cancer cell lines KB, MCF-7, and NCI-H187 with respective IC(50) values of 1.

Menisporopsin B, a new polyester from the seed fungus Menisporopsis theobromae BCC 4162.

A new linear polyester, menisporopsin B, along with the known macrocyclic polyester, menisporopsin A, was isolated from the seed fungus Menisporopsis theobromae BCC 4162. The structure of menisposopsin B was addressed primarily by spectroscopic analyses, and the stereochemistry was established by chemical correlation. Menisporopsin B exhibited antimalarial activity with an IC(50) value of 1.

A xanthocillin-like alkaloid from the insect pathogenic fungus Cordyceps brunnearubra BCC 1395.

Cordyformamide (4), the plausible biogenetic precursor of xanthocillin Y2, was isolated from a culture broth of the insect pathogenic fungus Cordyceps brunnearubra BCC 1395. Cordyformamide was found to exhibit activity against the malarial parasite Plasmodium falciparum K1 with an IC50 value of 18 microM, whereas it showed weak or no cytotoxicity.