Short-course parenteral antibiotic therapy for pyelonephritis in pregnancy.

A short-term course of an intravenous cephalosporin (cefuroxime) was used as therapy in 24 cases of pyelonephritis due to susceptible organisms in 23 pregnant women. Clinical cure was achieved in 96% of patients, and there were no adverse reactions to the drug. Bacteriologic cure was documented in 52% of those clinical cures, whereas 26% were considered to have bacterial colonization.

Acute bacterial endocarditis in pregnancy. A report of three cases.

Acute bacterial endocarditis, a fulminating disorder most often caused by Staphylococcus aureus, is uncommon in pregnancy. However, the frequency of this disease may be increasing due to the prevalence of intravenous drug abuse. Three cases occurred during pregnancy at Charity Hospital, New Orleans; all three patients were intravenous drug abusers.

Haemophilus influenzae implicated in puerperal infection.

We have described two cases of Haemophilus influenzae isolation, one from a patient with chorioamnionitis and one from a patient with bacteremia and endomyometritis. The first patient responded to cefoxitin and delivery, while the second patient failed to improve satisfactorily with clindamycin and tobramycin therapy, but responded to ampicillin.