[Effect of Prostanorm on the persistent potential of microorganisms isolated from patients with chronic bacterial prostatitis].

Aim: To determine the effect of the Prostanorm on the persistent potential of microorganisms isolated from the prostatic secretion of patients with chronic bacterial prostatitis.

Materials And Methods: In vitro experiments were carried out on uropathogens, isolated from prostate secretions in patients with chronic bacterial prostatitis, including Escherichia coli, Staphylococcus aureus, S. haemolyticus, S.

[Effect of Fitofron on the persistence factors of opportunistic pathogens in urine isolated from patients with urinary tract infections].

Aim: To perform an experimental evaluation of the effect of Phytofron, used for the treatment of urinary tract infections, on the ability of opportunistic pathogens to inactivate innate immunity factors (lysozyme, pro- and anti-inflammatory cytokines) and form biofilms.

Materials And Methods: In vitro experiments were carried out on clinical isolates from urine of patients with pyelonephritis and cystitis: Escherichia coli, Staphylococcus aureus, S. haemolyticus, S.

[Antibiotic resistance of strains of gram-positive cocci isolated from prostate secretion in men with chronic bacterial prostatitis].

Objective: to characterize the antibiotic resistance of gram-positive cocci strains isolated from the prostate secretion in men with chronic bacterial prostatitis at the level of phenotype and genotype.

Materials And Methods: Bacteria were isolated from the prostate secretion of men of reproductive age (20-45 years) with chronic bacterial prostatitis by conventional bacteriological method. The type of microorganisms was determined by MALDI-TOF mass spectrometry.

Heritage Speakers as Part of the Native Language Continuum.

We argue for a perspective on bilingual heritage speakers as native speakers of both their languages and present results from a large-scale, cross-linguistic study that took such a perspective and approached bilinguals and monolinguals on equal grounds. We targeted comparable language use in bilingual and monolingual speakers, crucially covering broader repertoires than just formal language. A main database was the open-access RUEG corpus, which covers comparable informal vs.

Deconstructing the Native Speaker: Further Evidence From Heritage Speakers for Why This Horse Should Be Dead!

The category "native speaker" is flawed because it fails to consider the diversity between the speaker groups falling under its scope, as highlighted in previous literature. This paper provides further evidence by focusing on the similarities and differences between heritage speakers (HSs) and monolingually-raised speakers (MSs) of their heritage and majority languages. HSs are bilinguals who acquire a family (heritage) language and a societal (majority) language in early childhood.

Genome Analysis of the Probiotic Strain Enterococcus faecium Ef79OSAU.

We report here the draft genome sequence of Enterococcus faecium strain Ef79OSAU, which was isolated from swine feces. The characteristics of strain Ef79OSAU reveal the absence of pathogenicity factors, a wide range of antimicrobial activity , and antilisteriosis activity . Analysis of the E.

Historical Review of Ethnopharmacology in Karelia (1850s-2020s): Herbs and healers.

Ethnopharmacological Relevance: The traditional medicine of various peoples populating Russia is strongly underrepresented in the international anthropological literature. In addition, it has a multicomponent structure, a long history of relations with official medicine, and is still a living system with many people using folk remedies and visiting ritual specialists.

Aim Of The Study: The article is a review of folk medicine in Karelia (north-west part of Russia) providing a short description of the history of medicine in this region and a comparison of folk medicine among Karelians and Russians.

[Characteristics of the pathogenic potential of Escherichia coli isolated from patients with calculous pyelonephritis].

Objective: Comparative phenotypic and genetic assessment of the pathogenic potential of E. coli strains isolated from patients with calculous pyelonephritis.

Materials And Methods: 78 strains of E.

Genomic Sequence of the Strain Enterococcus faecium ICIS 18.

We report here the draft genome sequence of strain ICIS 18, which was isolated from human feces. Analysis of the ICIS 18 genome revealed genes encoding resistance to metals, fluoroquinolones, and beta-lactam antibiotics.

[Biological properties of microorganisms isolated from the urine of patients with urolithiasis].

Aim: To define persistent properties and antibiotic resistance of microorganisms isolated from the urine of adult patient undergoing surgery for urolithiasis.

Materials And Methods: Urine specimens were obtained from the renal pelvis and urinary bladder during percutaneous nephrolithotripsy. Microorganisms that were isolated from the urine were examined for their persistent properties (anti-lysozyme activity, the ability of biofilm formation) and antibiotic resistance using photometric and bacteriological methods.

Genome Sequence of Enterococcus faecium Strain ICIS 96 Demonstrating Intermicrobial Antagonism Associated with Bacteriocin Production.

We report here the complete genome sequence of strain ICIS 96, which was isolated from the feces of a horse. Bacteriological characterization of strain ICIS 96 revealed the absence of pathogenicity factors, while its spectrum of antagonistic activity was found to be broad, having activities associated with both Gram-positive and Gram-negative bacteria. Analysis of the ICIS 96 genome revealed five genes associated with antimicrobial activity (enterocin [ent] A, ent B, lactobin A/cerein 7b, and ent L50 A/B).

Antimicrobial activity of the indolicidin-derived novel synthetic peptide In-58.

Natural peptides with antimicrobial activity are extremely diverse, and peptide synthesis technologies make it possible to significantly improve their properties for specific tasks. Here, we investigate the biological properties of the natural peptide indolicidin and the indolicidin-derived novel synthetic peptide In-58. In-58 was generated by replacing all tryptophan residues on phenylalanine in D-configuration; the α-amino group in the main chain also was modified by unsaturated fatty acid.

[Structure of microorganism species cultured from urine of urolithiasis patients].

Aim: To investigate the incidence of microorganisms of different taxonomic groups and their associations in the pelvic and bladder urine of adult urolithiasis patients.

Materials And Methods: A bacteriological method and metagenomic sequencing were used to investigate the bacterial spectrum of microflora cultured from pelvic and bladder urine sampled during surgical interventions in urolithiasis patients.

Results: The both microbiotas had approximately the same spectrum, but in 26.

[BIOLOGICAL ACTIVITY OF ANTIMICROBIAL PEPTIDES FROM CHICKENS THROMBOCYTES].

Aim: Isolation and study of biological activity of antimicrobial peptides from chickens thrombocytes.

Materials And Methods: Peptides from chickens thrombocytes, obtained by reverse-phase high-performance liquid chromatography method with stepped and linear gradients of concentration increase of the organic solvent were used in the study. Their antimicrobial activity was determined by microtitration method in broth; mechanism of biological effect--by using fluorescent spectroscopy method with DNA-tropic dyes.

[Biological properties of primary HIV-1 isolates with varying serotype].

Russian HIV variants with common (rapid/high SI and slow/low NSI) and rare (slow/low SI and rapid/high NSI) phenotypes are described. SI variants demonstrate a higher p24 concentration level than serotype-independent NSI. The majority of SI variants belonging to A, B, and C serotypes were isolated from patients with mainly stage B3.

[A replaceable nonfrictional membrane filter for the prevention of cell culture contamination].

A changeable membrane filter preventing the friction between moving parts and the membrane during tight screwing of a culture flask is proposed.

[Analysis of the biological characteristics of primary HIV-1 isolates using the main components method].

The principal component method is verified for analysis of categorized biological characteristics of HIV-1 variants. Thirty wild isolates of HIV-1 are studied. The method notably facilitated comparative analysis of a large scope of experimental data.

[Electrical impedance tomography in pulmonology].

Application of a modern method of introscopy--electroimpedance tomography (EIT) for diagnosis of different types of lung diseases is described. The EIT system including measurement and collecting data devices, 16-electrodes array and IBM PC 486 computer was used. The results of analysis of electrotomograms have demonstrated that the EIT-system can be introduced for detecting abnormal lung fluid levels, pulmonary edema, diagnosis of lung cancer, emphysema, pleuritis, hydrothorax, sarcoidosis.

[Suppression of the reproduction of the human immunodeficiency virus (HIV) with a cytokine-like antiviral factor].

Cytokine-like antivirus factor, obtained from the culture fluid of chick embryo fibroblasts, was found to possess inhibitory activity with respect to HIV-1 (strains 1/Zmb and RF). The treatment of HIV-infected cell culture with cytokine-like factor was accompanied by a decrease in the cytopathic effect of the agent without manifestations of cytotoxicity. The combined use of the cytokine-like factor and azidothymidine at near-threshold concentrations was not accompanied by an increase in the antivirus effect, observed after the use of each preparation separately.

[Respiratory and hemodynamic disorders in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].

After examination of cardiorespiratory function in 10 males exposed to Chernobyl accident unfavorable factors at the age of 31-45 years suffering from chronic obstructive bronchitis (7 cases) and mixed bronchial asthma (3 cases) it was established that the patients had ventilation disorders of mixed genesis (moderate obstructive and respiratory affections), frequently occurring decreased specific diffusion (DLCO/Va) in normal total diffusion capacity of the lungs, inefficient gas exchange, midly declined left ventricular pump capacity and contractility. In the above patients a relationship was found between parameters of central hemodynamics assessed at echo-CG and severity of ventilation impairment and respiratory insufficiency.

[Identification of immunoreactive epitopes in proteins coded by gag, env, and pol genes of the type I human T-lymphotropic virus (HTLV-I) using synthetic peptides].

Reactivity of 26 synthetic peptides that comprise 12 to 26 amino acid residues corresponding to segments of the gag p19, env gp46, and pol proteins of human T-lymphotropic virus type I toward 31 positive sera was studied using enzyme-linked immunosorbent assay. Specific reactivity with high titers of antibodies (presented in reciprocal dilution values) was detected for the synthetic peptides corresponding to fragments 110-130 and 100-130 (titers up to 4050) of p19, 174-197 (up to 800), 186-201 (up to 4050), 191-215 (up to 1350), 242-257 (up to 800), and 272-292 (up to 450) of gp46. Immunoreactivity of seven peptides, fragments of pol-proteins, was weak.