Real-World Experience in Tricuspid Transcatheter Edge-to-Edge Repair: Transcatheter Tricuspid Valve Repair in Spain Registry.

Background: Significant tricuspid regurgitation (TR) is associated with increased morbidity and mortality. The development of transcatheter valve repair therapies has opened a wide range of opportunities for treatment of patients with high surgical risk. Real-world data might improve patient selection and outcome.

Transcatheter edge-to-edge repair in severe mitral regurgitation following acute myocardial infarction - aetiology-based analysis.

Aims: To evaluate the association between transcatheter edge-to-edge repair (TEER) and outcomes in patients with significant mitral regurgitation (MR) following acute myocardial infarction (MI), focusing on the aetiology of acute post-MI MR in high-risk surgical patients.

Methods And Results: The International Registry of MitraClip in Acute Mitral Regurgitation following Acute Myocardial Infarction (IREMMI) includes 187 patients with severe MR post-MI managed with TEER. Of these, 176 were included in the analysis, 23 (13%) patients had acute papillary muscle rupture (PMR) and 153 (87%) acute secondary MR.

Social Representation, Stereotypes and Social Identity Pertaining to Nursing Through Children's Drawings: A Qualitative Study.

The aim of this study is to explore children's depictions of nursing professionals, identifying shared and differential visual and symbolic elements as a function of gender, the period during which the drawing was made (pre-/postpandemic) and whether or not one has a relative who works in the same profession. Drawing circumnavigates the limits imposed by literacy and gives a voice to children who are able to express their personal feelings and subconscious through the drawn object. Theories of social representations and identity strive to explore the way in which children perceive and value the role of nurses in society.

Toward understanding grapevine responses to climate change: a multistress and holistic approach.

Recent research has extensively covered the effects of climate change factors, such as elevated CO2, rising temperatures and water deficit, on grapevine (Vitis spp.) biology. However, the assessment of the impacts of multiple climate change-related stresses on this crop remains complex due to the large number of interactive effects among environmental factors and the regulatory mechanisms that underlie these effects.

Sex related disparities after complex percutaneous coronary interventions.

Introduction: Complex Percutaneous coronary intervention (PCI) for the treatment of ischemic heart disease has increased significantly. We aimed to evaluate sex-related differences in patients undergoing complex PCI.

Methods: single-center prospective observational study including patients undergoing complex PCI between 2017 and 2023.

Impact of Optimal Procedural Result After Transcatheter Edge-to-Edge Tricuspid Valve Repair: Results From TRI-SPA Registry.

Background: Procedural success following tricuspid transcatheter edge-to-edge repair (TEER) has been defined variably over time; however, the consequences of achieving a tricuspid regurgitation (TR) grade of 0/1+ are still unclear.

Objectives: This study aimed to assess the predictors and prognostic impact of achieving TR 0/1+ after TEER and its role in clinical events.

Methods: This multicenter registry included patients undergoing tricuspid TEER in 15 Spanish centers from June 2020 and May 2023.

Grapevine varieties show different sensitivities to flavonoid alterations caused by high temperatures under two irrigation conditions.

This study aimed to assess the response of four red grapevine (Vitis vinifera L.) varieties to elevated temperature, drought and their combination, focusing on the concentration and profile of grape flavonoids. Fruit-bearing cuttings of Tempranillo, Cabernet Sauvignon, Merlot and Grenache grew in greenhouses under, either ambient temperature (T) or ambient temperature + 4 °C (T+4).

Storage Optimization of Transmission Holographic Gratings in Photohydrogels.

The development and optimization of holographic materials represent a great challenge today. These materials must be synthesized according to the characteristics that are desirable in photonic devices whose application is the object of investigation. In certain holographic sensors and biosensors, it is essential that the recording material be stable in liquid media.

Sex-Related Differences in Life Expectancy Compared to General Population after Surgery for Ascending Aortic Aneurysm.

: Understanding sex-based differences in cardiovascular outcomes is paramount to improving clinical outcomes. Surgery is an aggressive but effective therapy for ascending aortic aneurysm. We sought to determine if being a woman is a risk factor for long-term mortality after this surgery.

PCSK9 gene variations in the clinical setting of premature cardiovascular disease: A critical appraisal.

Introduction: Information about PCSK9 gene variations and its association with cardiovascular (CV) disease is controversial. We aimed to evaluate 3 reported polymorphisms in PSCK9 in a cohort of young patients with myocardial infarction with ST segment elevation (STEMI).

Methods: Retrospective study of consecutive patients with premature STEMI (2018-2023).

The Usefulness of Intraepithelial Lymphocyte Immunophenotype Testing for the Diagnosis of Coeliac Disease in Clinical Practice.

Background: The diagnosis of coeliac disease (CD) in adults is based on clinical, serological and histological criteria. The inappropriate performance of intestinal biopsies, non-specificity of mild histological lesions and initiation of a gluten-free diet (GFD) before biopsy may hamper the diagnosis. In these situations, determining the intraepithelial lymphogram of the duodenum by flow cytometry (IEL-FC) can be helpful.

A synchronized, large-scale field experiment using Arabidopsis thaliana reveals the significance of the UV-B photoreceptor UVR8 under natural conditions.

This study determines the functional role of the plant ultraviolet-B radiation (UV-B) photoreceptor, UV RESISTANCE LOCUS 8 (UVR8) under natural conditions using a large-scale 'synchronized-genetic-perturbation-field-experiment'. Laboratory experiments have demonstrated a role for UVR8 in UV-B responses but do not reflect the complexity of outdoor conditions where 'genotype × environment' interactions can mask laboratory-observed responses. Arabidopsis thaliana knockout mutant, uvr8-7, and the corresponding Wassilewskija wild type, were sown outdoors on the same date at 21 locations across Europe, ranging from 39°N to 67°N latitude.

Clinical impact of complex percutaneous coronary intervention in the pre-TAVR workup.

Introduction And Objectives: In patients undergoing percutaneous coronary intervention (PCI) in the workup pre-transcatheter aortic valve replacement (TAVR), the clinical impact of coronary revascularization complexity remains unknown. This study sought to examine the impact of PCI complexity on clinical outcomes after TAVR in patients undergoing PCI in the preprocedural workup.

Methods: This was a multicenter study including consecutive patients scheduled for TAVR with concomitant significant coronary artery disease.

Survival analysis and gender differences in hypertrophic cardiomyopathy proband patients referred for genetic testing.

Background: Hypertrophic cardiomyopathy (HCM) is believed to have low overall mortality rate, that could be influenced by gender, particularly among probands. We aimed to evaluate the survival rates and possible gender differences in a homogeneous cohort of HCM proband patients, referred for genetic testing, from the same geographical area, without differences in medical care access nor clinical referral pathways.

Methods: we compared the mortality rates of a cohort of consecutive HCM probands referred for genetic testing (2000-2022), from a Spanish region (xxx1) with a centralized genetic testing pathway, with its control reference population by Ederer II method.

Late bleeding events in TAVI patients receiving vitamin K antagonists or direct oral anticoagulants.

Introduction And Objectives: The optimal chronic antithrombotic regimen for patients with atrial fibrillation undergoing transcatheter aortic valve implantation (TAVI) remains uncertain. Our aim was to compare the incidence of late bleeding events between patients on direct oral anticoagulants (DOACs) and those on vitamin-K antagonists (VKA).

Methods: This single-center observational study included TAVI patients requiring oral anticoagulation at discharge between 2015 and 2021.

Arbuscular Mycorrhizal Fungi Improve the Performance of Tempranillo and Cabernet Sauvignon Facing Water Deficit under Current and Future Climatic Conditions.

Climate change (CC) threatens Mediterranean viticulture. Rhizospheric microorganisms may be crucial for the adaptation of plants to CC. Our objective was to assess whether the association of two grapevine varieties with arbuscular mycorrhizal fungi (AMF) increases grapevine's resilience to environmental conditions that combine elevated atmospheric CO, increased air temperatures, and water deficit.

Photopolymer Holographic Lenses for Solar Energy Applications: A Review.

Holographic lenses (HLs) are part of holographic optical elements (HOE), and are being applied to concentrate solar energy on a focal point or focal line. In this way, the concentrated energy can be converted into electrical or thermal energy by means of a photovoltaic cell or a thermal absorber tube. HLs are able to passively track the apparent motion of the sun with a high acceptance angle, allowing tracking motors to be replaced, thus reducing the cost of support structures.

Hemodynamic performance of self-expandable transcatheter aortic valve replacement systems during valve deployment.

Objectives: Little is known about valve hemodynamic performance during the Evolut and Neo deployment course. We aimed to evaluate transvalvular mean and peak-to-peak gradients over several intraprocedural timepoints during TAVR with Evolut PRO+ (Medtronic) and Neo (Boston Scientific) systems.

Methods: This was single-center pilot sub-study from the SavvyWire EFficacy and SafEty in Transcatheter Aortic Valve Implantation Procedures (SAFE-TAVI) trial.