Publications by authors named "Pascoe M"

Background: Speech-language pathologists (SLPs) in non-English speaking countries face challenges when assessing children for speech sound disorders (SSD). Exploring their clinical challenges in service delivery-along with their problem-solving approaches-may contribute to the development of instruments for clinical use in such settings.

Aim: The study aimed to explore assessment methods used by Iranian SLPs to identify children with SSD.

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  • Radiation therapy is a common treatment for primary brain tumors, but it may lead to significant sleep disorders that haven't been fully explored.
  • A systematic review analyzed 38 studies involving nearly 2,948 patients, finding a high incidence of sleep disturbances particularly from the end of radiation to six months afterward, linked to radiation dosage.
  • The review calls for more research on sleep disorders in patients with primary brain tumors and suggests that pharmacological interventions can help manage sleep symptoms, despite inconsistencies in how these symptoms are reported across studies.
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  • Primary care clinicians can effectively screen for sleep issues, assist patients when possible, and refer complex cases to specialists.
  • Poor sleep impacts nearly all organ systems and contributes to various health problems, highlighting the need for routine examination of sleep quality and duration in primary care.
  • The text discusses ways to enhance support and compensation for primary care providers to improve their ability to address patients' sleep concerns through meaningful conversations.
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Thiamine-responsive megaloblastic anaemia (TRMA) is a rare autosomal recessive disorder characterised by the clinical triad of megaloblastic anaemia, sensorineural hearing loss and diabetes mellitus (DM) in young patients. We present a case of a young man with type 1 DM who presented with pancytopenia of unclear aetiology, initially attributed to a COVID-19 infection. After obtaining a bone marrow biopsy and pursuing genetic testing, two pathogenic variants of the SLC19A2 gene consistent with TRMA were discovered in this patient.

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  • Untreated obstructive sleep apnea (OSA) in acute ischemic stroke (AIS) patients increases health risks, making diagnosis and treatment difficult in this demographic.
  • The study involved 27 AIS inpatients at Cleveland Clinic, where portable monitoring (PM) was used to identify OSA, and those with severe cases were offered therapy called auto-titrating positive airway pressure (APAP).
  • Despite high ratings for ease of use of the PM device, only a small percentage of patients continued using the APAP treatment consistently, revealing significant barriers and the need for more research on better screening and treatment strategies for OSA in AIS patients.
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  • Sleep-wake disturbances are prevalent among primary brain tumor patients, and this study explores the relationship between patient-reported outcomes (PROs) and data from smart wearables like Fitbits over a 4-week period.
  • Fifty-four patients participated, wearing Fitbits to track their sleep patterns and completing various PROs at the start and end of the study, showing high compliance and reliability in the data collected.
  • Results indicated that while some patients experienced significant improvements in sleep disturbance, a notable correlation was found between wake after sleep onset and sleep disturbance, highlighting a need for further research into sleep mechanics in this patient population.
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Anatomy with human dissection may help to develop respect for the human body and professionalism; however, dissection may worsen students' attitudes about body weight and adiposity. The purpose of this study was to measure weight bias among Doctor of Physical Therapy (DPT) students enrolled in gross anatomy and determine if, and how the experience of dissection impacts weight bias. Ninety-seven DPT students (70 University of Colorado [CU], 27 Moravian University [MU]) were invited to complete a survey during the first and final weeks of their anatomy course.

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Background:  South African children from low-income households are at higher risk of cognitive-linguistic difficulties because of multiple risk factors. Early language stimulation minimises the effects of risk factors and prepares children for literacy and learning. Understanding caregivers' perceptions of language stimulation is important because perceptions shape practices, which determine child language outcomes.

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Osteoarthritis is a leading cause of chronic pain and is associated with high rates of depression. Physical activity reduces depression symptoms and pain levels. It remains unknown if physical activity is associated with lower symptoms of depression irrespective of pain levels in individuals with osteoarthritis.

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Background: Identification of transthyretin cardiac amyloidosis (ATTR-CA) patients is largely based on pattern recognition by providers, and this can be automated through electronic medical systems (EMR).

Methods: All patients in a large academic hospital with age > 60, ICD-10 code for chronic diastolic heart failure and no previous diagnosis of any amyloidosis were included. An Epic EMR scoring logic assigned risk scores to patients for ICD-10 and CPT codes associated with ATTR-CA, as follows: carpal tunnel syndrome (score 5), aortic stenosis/TAVR (5), neuropathy (4), bundle branch block (4), etc.

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Transitioning out of elite sports can be a challenging time for athletes. To illuminate the gaps and opportunities in existing support systems and better understand which initiatives may have the greatest benefit in supporting athletes to transition out of elite sport, this study examined the lived experience of retired elite Australian athletes. Using a sequential mixed-methods approach, quantitative data were collected via a self-report online survey, while qualitative data were collected via semistructured interviews.

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Background: Qualitative evidence points to the importance of both mental health-related barriers and benefits to exercise in chronic pain, yet this bidirectional relationship has not been established quantitatively.

Methods: 89 adults with chronic pain (75 female, Age: M = 34.7, SD=13.

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Background: Several studies have assessed whether physical activity interventions can reduce substance use in young people at risk of problematic substance use. This report identifies and describes the reporting of implementation characteristics within published studies of physical activity interventions for young people at risk of problematic substance use and provides recommendations for future reporting.

Methods: Reported implementation strategies (including intervention manualization), barriers, implementation fidelity, and personnel acceptance were extracted from studies of physical activity interventions for young people aged 12-25 years at risk of problematic substance use that were included in a previous systematic review of intervention efficacy.

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Background: Human papillomavirus (HPV) vaccination programs are a key intervention in protecting individuals against HPV-related disease. HIV1-infected individuals are at increased risk of HPV-associated cancers. This study was conducted to evaluate the potential role of prophylactic HPV vaccines in preventing new HPV infections among participants with perinatally acquired HIV who received the quadrivalent HPV vaccine at least five years before this study.

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  • - The adolescent and young adult (AYA) cancer population, specifically those aged 15-39 with primary brain tumors, faces significant challenges in their treatment, trial participation, and overall quality of life, despite being increasingly recognized.
  • - A systematic literature review identified 68 relevant studies that highlighted 11 specific challenges related to clinical trials for AYAs, including issues like tumor biology, diagnostic delays, and limited trial availability.
  • - The study concludes that the unique needs of AYAs with CNS cancers are often overlooked, emphasizing the necessity for more targeted research and tailored care to enhance their treatment outcomes and trial involvement.
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Background: The demand for orthopedic specialist consultations for patients with osteoarthritis in public hospitals is high and continues to grow. Lengthy waiting times are increasingly affecting patients from low socioeconomic and culturally and linguistically diverse backgrounds who are more likely to rely on public health care.

Objective: This study aimed to co-design a digital health intervention for patients with OA who are waiting for an orthopedic specialist consultation at a public health service, which is located in local government areas (LGAs) of identified social and economic disadvantage.

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A detailed comparison of the capabilities of electron microscopy and nano-infrared (IR) microscopy for imaging microbial nanostructures has been carried out for the first time. The surface sensitivity, chemical specificity, and non-destructive nature of spectroscopic mapping is shown to offer significant advantages over transmission electron microscopy (TEM) for the study of biological samples. As well as yielding important topographical information, the distribution of amides, lipids, and carbohydrates across cross-sections of bacterial (, ) and fungal () cells was demonstrated using PiFM.

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Prematurity may produce long-term complications in the physical and cognitive development of infants. There is a need for interventions that can improve feeding and reduce the length of NICU stay and separation time between the infant and mother. This study aimed to explore the clinical effect of premature infant oral motor intervention [PIOMI] combined with music therapy [MT] on feeding progression in premature infants.

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Aim: This systematic review investigates behaviour change techniques in interventions promoting physical activity for young people aged 12-25 years at heightened risk of problematic substance use, and the effect of these techniques on physical activity participation and substance use outcomes.

Methods: Four databases (PsycINFO, CINAHL, SPORTDiscus and Medline) were searched between November 2020 and November 2022 for randomized and non-randomized controlled studies according to inclusion criteria. Meta-analyses were calculated using weighted, standardized averages of effect sizes (Hedges' g).

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Chemical biocides are used for the prevention and control of infection in health care, targeted home hygiene or controlling microbial contamination for various industrial processes including but not limited to food, water and petroleum. However, their use has substantially increased since the implementation of programmes to control outbreaks of methicillin-resistant Staphylococcus aureus, Clostridioides difficile and severe acute respiratory syndrome coronavirus 2. Biocides interact with multiple targets on the bacterial cells.

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Autism spectrum disorder is characterized by social communication difficulties and social skills abilities that are significantly differ from neurotypical populations as well as restricted and repetitive behaviors and interests. Furthermore, many autistic youth experience co-occurring conditions, with one of the most common being depression. This depression is suggested to be, in part, the result of the relative social isolation experienced by autistic youth.

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Purpose: To date there are no studies of speech sound acquisition in Laki, a language spoken in western regions of Iran. Thus, we set out a pilot study to investigate the speech development of 56 first language Laki-speaking children (aged 3-5 years).

Method: Single words were elicited through a picture naming test specifically developed for this study.

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Background: Musculoskeletal conditions, including osteoarthritis (OA), are a leading cause of disability and chronic pain, and are associated with high rates of comorbid depression. However, signs of depression are often masked by pain. The aim of this study was to determine the prevalence and severity of depression and pain in individuals awaiting specialist orthopaedic consultation.

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Objectives: We examined age, residence, education and wealth inequalities and their combinations on cervical precancer screening probabilities for women. We hypothesised that inequalities in screening favoured women who were older, lived in urban areas, were more educated and wealthier.

Design: Cross-sectional study using Population-Based HIV Impact Assessment data.

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Introduction: Apathy is one of the most common neuropsychiatric manifestations in Parkinson's disease (PD). Recent proposals consider apathy as a multidimensional construct, which can manifest in behavioral, cognitive, emotional, and/or social dimensions. Apathy also overlaps conceptually and clinically with other non-motor comorbidities, particularly depression.

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