First HSV-1 non primary genital herpes in two patients.

First HSV-1 genital episodes in HSV-2 infected patients however, had never been demonstrated until the 2 cases we observed. This scarcity could reflect the lower impact of HSV-2 on western populations but questions the existence of cross-protection between viral types.

Etiology of genital ulcer disease. A prospective study of 278 cases seen in an STD clinic in Paris.

Objectives: The goal of this study was to identify the causes and factors associated with genital ulcer disease (GUD) among patients attending a sexually transmitted disease (STD) clinic in Paris.

Methods: This study was a prospective investigation of GUD cases. Data were collected from 1995 to 2005.