Publications by authors named "Pascal del Giudice"

Article Synopsis
  • - Secondary bacterial infections commonly occur in skin conditions like atopic dermatitis, ectoparasitosis, and varicella zoster, primarily involving Staphylococcus aureus and Streptococcus pyogenes, with occasions of Gram-negative infections as well.
  • - Factors that promote these infections include changes to the skin barrier, itchiness, and specific environmental influences, which can vary based on the patient's location and the type of dermatosis.
  • - Effective prevention and treatment hinge on managing the underlying skin condition, maintaining proper skin hygiene, and in cases of recurrence, addressing S. aureus colonization.
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We describe a rare case of early Lyme borreliosis in France caused by Borrelia spielmanii, which manifested as a large erythema chronicum migrans rash. The patient completely recovered after a 15-day course of amoxicillin. Absence of pathognomonic signs prevented distinguishing B.

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Background: Adverse pregnancy outcomes (APO) occur in 35% of patients with pemphigoid gestationis (PG). No biological predictor of APO has been established yet.

Objectives: To assess a potential relationship between the occurrence of APO and the serum value of anti-BP180 antibodies at the time of PG diagnosis.

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We report intrafamilial transmission of monkeypox virus to all members of a family (father, mother, and 2 children). Case reports in young children have been extremely rare during the 2022 mpox outbreak. Their clinical signs were mild, and clinical diagnosis would be difficult without knowledge of the father's monkeypox virus infection.

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Article Synopsis
  • Ivermectin is a safe and effective treatment for several tropical diseases but is not recommended for children under 15 kg, limiting access to necessary care.
  • A systematic review and individual-level patient data meta-analysis were conducted on past studies from 1980 to 2019 to evaluate the drug’s safety in this demographic.
  • Out of 1,088 treated children, only 1.4% experienced mild, self-limiting adverse events, indicating that the risks associated with ivermectin in this group are minimal.
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Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012-2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation.

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We present a case of a 22-month-old girl who had 2 episodes of cutaneous larva migrans 2 months apart after returning from a tropical area, despite a single exposure period.

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Staphylococcus aureus is the most common pathogen involved in skin infections worldwide, regardless of the patient's age, the climate or geographical area. The main skin clinical manifestations can be linked to a few toxins produced by the bacteria, which give rise to a rich and varied clinical spectrum. Panton Valentine leucocidin, exfoliatins, enterotoxins and toxin shock syndrome toxin 1 are the main toxins involved in most dermatological manifestations associated with S.

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We described nosocomially clustered cases of measles secondary to a nonvaccinated index case occurring in a teenage psychiatric unit despite optimum vaccine coverage. Surveillance of this fully vaccinated closed cohort showed a 7% attack rate. Vaccination limited the risk of complicated measles and the onset of a large outbreak.

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Cutaneous larva migrans is a dermatitis, typically acquired in warm tropical or sub-tropical countries, caused by migration of the larvae of nematodes (hookworm; mainly Ancylostoma braziliense and, occasionally, Ancylostoma caninum or Uncinaria stenocephala), which are parasitic on animals such as cats and dogs, into the patient's skin. The larvae penetrate the skin after contact with infected soil and cause a typical creeping eruption. Patients with cutaneous larva migrans seen in Europe have usually acquired the disease following a stay in a tropical or sub-tropical area.

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Bacteraemias are life-threatening conditions that require rapid care and antibiotherapy. Dermatological signs might help in deciding the most relevant treatment. The aim of this study was to determine the prevalence and clinical characteristics of cutaneous manifestations in hospitalized patients with bacteraemia.

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Article Synopsis
  • Treponema pallidum subsp. pallidum, the bacteria causing syphilis, was genetically analyzed in 133 clinical samples from patients in France between 2010-2016 using a Multilocus Sequence Typing system.
  • The study identified 18 different allelic profiles among 112 fully typed samples, revealing notable genetic diversity, including several novel alleles.
  • Results showed that patients infected with Nichols-like strains were generally older and diagnosed with secondary syphilis more frequently, with specific genetic mutations linked to antibiotic resistance present in certain allelic profiles.
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