Publications by authors named "Pascal Hot"

A positivity effect in attention (i.e., an attentional bias in favor of positive over negative stimuli) has been frequently reported in older adults.

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The prevailing view in human cognitive neuroscience associates the medial temporal lobes (MTLs) with declarative memory. Compelling experimental evidence has, however, demonstrated that these regions are specialized according to the representations processed, irrespective of the cognitive domain assessed. This account was supported by the study of patients with bilateral medial temporal amnesia, who exhibit impairments in perceptual tasks involving complex visual stimuli.

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The aim of this study was to evaluate the prevalence of early life stress (ELS) in a population with inflammatory bowel diseases (IBD) and to estimate its burden on mental, physical, and digestive health. Ninety-three participants with IBD were asked to anonymously complete questionnaires (Childhood Trauma Questionnaire-Short Form, Early Life Event Scale, Perceived Stress Scale, Hospital Anxiety and Depression Scale, Ways of Coping Checklist, Gastro-Intestinal Quality of Life Index questionnaire, and ad hoc questions about symptoms). The prevalence of patients with IBD who were exposed to at least one childhood abuse was 53%.

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Impairments in decision-making have been reported in brain-damaged (stroke/traumatic brain injury) patients with a wide range of lesion sites. Here, we propose that the performances of patients in complex sequential decision-making (DM) tasks can be explained by their negative affectivity, leading to deliberative processing associated with poor DM performances. We assumed that a slow-paced breathing (SPB) training, by reducing negative affectivity would improve performances in a complex DM task.

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Background: Functional neurological disorders (FND), a subtype of functional disorders (FD), are a frequent motive for neurology referrals. The various presentations and the unknown physiopathology of FD have led to the multiplication of terms describing these disorders over the years.

Methods: We examined the FD-related articles published from 1960 to 2020 in PubMed and PsycINFO databases.

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Human physiological reactions to the environment are coordinated by the interactions between brain and viscera. In particular, the brain, heart, and gastrointestinal tract coordinate with each other to provide physiological equilibrium by involving the central, autonomic, and enteric nervous systems. Recent studies have demonstrated an electrophysiological coupling between the gastrointestinal tract and the brain (gut-brain axis) under resting-state conditions.

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An emotion-induced memory trade-off effect is frequently reported when participants have to memorize complex items that include both neutral and emotional features. This bias corresponds to better remembering of central emotional information accompanied by poor performance related to neutral background information. Although the trade-off effect has been mainly associated with attentional bias toward emotional content, findings suggest that other non-attentional cognitive processes could also be involved.

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The functional organisation of the medial temporal lobe (MTL) has long been described on the basis of cognitive processes such as recollection or familiarity. However, this view has recently been challenged, and researchers have proposed decomposing cognitive phenomena into representations and operations. According to the representational view, representations, such as scenes for the hippocampus and objects for the perirhinal cortex, are critical in understanding the role of MTL regions in cognition.

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Older adults tend to be in a more positive mood than young adults, and tend to remember positive information more often than negative information, yet the link between their positive mood and their positive memory bias has not often been explored. In this study, we manipulated young and older adults' moods prior to their completing an emotional memory task. For mood manipulation, young ( = 147) and older ( = 111) adults viewed a positive, negative, or neutral video lasting 3 min.

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The fast reaction of the autonomic nervous system (ANS) to an emotional challenge (EC) is the result of a functional coupling between parasympathetic (PNS) and sympathetic (SNS) branches. This coupling can be characterized by measures of cross-correlations between electrodermal activity (EDA) (under the influence of the SNS) and the RR interval (the interval between R peaks) (under the influence of the PNS and the SNS). Significant interindividual variability has previously been reported in SNS-PNS coupling in emotional situations, and the present study aimed to identify interindividual cross-correlation variability in ANS reactivity.

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Impairments of emotional processing have been reported in Alzheimer's disease (AD), consistently with the existence of early amygdala atrophy in the pathology. In this study, we hypothesized that patients with AD might show a deficit of orientation toward emotional information under conditions of visual search. Eighteen patients with AD, 24 age-matched controls, and 35 young controls were eye-tracked while they performed a visual search task on a computer screen.

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A growing body of evidence suggests that emotional states under which individuals perform decision-making tasks modulate performance. Studies have mainly reported that negative emotions can differentially increase or decrease performance by modulating feedback processing. In contrast, differential influences of specific emotions inside positive valence have been poorly investigated.

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Objectives: Refreshing, or the act of briefly foregrounding recently presented but now perceptually absent representations, has been identified as a possible source of age differences in working memory and episodic memory. We investigated whether the refreshing deficit contributes to the well-known age-related deficit for retrieving nonsemantic associations, but has no impact on existing semantic associations.

Method: Younger and older adults judged the relatedness of stimulus word pairs (e.

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We report two patients suffering from drug-resistant temporal lobe epilepsy to show how their neuroplasticity can be apprehended using a multimodal, integrative and clinically relevant approach. This is a proof of concept based on using multimodal data including: (1) white matter structural connectivity (DTI) of the main tracts involved in language and memory; (2) neurophysiological biomarkers (fMRI-BOLD signal and LI lateralization indices); and (3) cognitive scores as measured during the neuropsychological assessment. We characterized tri-modal data for each patient using a descriptive integrative approach, in terms of reorganization and by comparing with a group of healthy participants.

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Emotional stimuli are often more semantically interrelated and relatively distinct than neutral stimuli. These factors can enhance memory for emotional stimuli in young adults, but their effects in older adults-and on the age-related positive memory bias-remain unknown. In the present article, we tested whether item relatedness and distinctiveness affect emotional memory in young adults (Exps.

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Unlabelled: Background/Study Context: To explain the high levels of well-being reported by older adults, socioemotional selectivity theory suggests that emotion regulation becomes more automated with age. Hence, the objective of the present study was to determine whether automatic emotion regulation becomes indeed more efficient with age, as controlled regulation becomes less efficient. We tested this hypothesis with regard to a specific emotion regulation strategy, expressive suppression, and a discrete emotion: disgust.

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Objectives: Numerous studies reported an age-related deficit in verbal working memory (WM). Beyond the well-established general factors of cognitive aging, the alteration of the specific WM maintenance mechanisms may account for this deficit. This paper aims to investigate the hypothesis that WM attentional maintenance is impaired with age.

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Emotional deficits have been repetitively reported in Alzheimer's disease (AD) without clearly identifying how emotional processing is impaired in this pathology. This paper describes an investigation of early emotional processing, as measured by the effects of emotional visual stimuli on a saccadic task involving both pro (PS) and anti (AS) saccades. Sixteen patients with AD and 25 age-matched healthy controls were eye-tracked while they had to quickly move their gaze toward a positive, negative, or neutral image presented on a computer screen (in the PS condition) or away from the image (in the AS condition).

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Understanding the factors that make working memory (WM) traces stable over time is important because WM is the keystone of general cognitive achievement. Two views of attentional WM maintenance have been suggested to account for the long-term retention of WM information. First, the distractors in a WM task are thought to foster the creation of episodic memory cues through covert retrieval.

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Age-related differences in neural correlates underlying implicit and explicit emotion processing are unclear. Within the framework of the Frontoamygdalar Age-related Differences in Emotion model (St Jacques et al., 2009), our objectives were to examine the behavioral and neural modifications that occur with age for both processes.

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Psychogenic nonepileptic seizures (PNES) are paroxysmal attacks that can imitate epileptic seizures but do not have a neurological origin. There has been mounting interest these last few years to unravel psychological and neuronal factors that contribute to the development of PNES. The objective of this review is twofold.

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In this functional magnetic resonance imaging (fMRI) study, we evaluated the effect of self-relevance on cerebral activity and behavioral performance during an incidental encoding task. Recent findings suggest that pleasantness judgments reliably induce self-oriented (internal) thoughts and increase default mode network (DMN) activity. We hypothesized that this increase in DMN activity would relate to increased memory recognition for pleasantly-judged stimuli (which depend on internally-oriented attention) but decreased recognition for unpleasantly-judged items (which depend on externally-oriented attention).

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The aim of this study was to examine the ultradian dynamic of emotional processing in men. Event-related potentials were recorded while participants watched different sets of unpleasant and neutral pictures every 15 min for 3 h. Emotional feelings induced by unpleasant pictures were also assessed with self-rating scales at the end of each picture set.

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Prominent disturbances in the experience, expression, and emotion recognition in patients with schizophrenia have been relatively well documented over the last few years. Furthermore, sex differences in behavior and brain activity, associated with the processing of various emotions, have been reported in the general population and in schizophrenia patients. Others proposed that sex differences should be rather attributed to testosterone, which may play a role in the etiology of schizophrenia.

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Current research suggests that amygdalar volumes in patients with Alzheimer's disease (AD) may be a relevant measure for its early diagnosis. However, findings are still inconclusive and controversial, partly because studies did not focus on the earliest stage of the disease. In this study, we measured amygdalar atrophy in 48 AD patients and 82 healthy controls (HC) by using a multi-atlas procedure, MAPER.

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