[Correction of disorders of phosphorus metabolism after operations on the abdominal organs].

Hypophosphatemia and decreased content of ATP, 2,3-DPG in erythrocytes were found in 147 patients operated upon organs of the abdominal cavity. Hypophosphatemia was more pronounced after operations for ulcer disease of the stomach and duodenum, acute pancreatitis and commissural ileus. An intravenous injection of potassium dihydrogen phosphate++ prevents the development of hypophosphatemia and concomitant decrease of the content of nonorganic phosphorus, ATP, 2,3-DPG in erythrocytes and may improve the postoperative period in these patients.

[Disordered phosphorus metabolism and its correction in the acute period of severe craniocerebral trauma].

Marked hypophosphatemia was discovered in 78 patients in the acute period of severe craniocerebral injury. It led to a decrease of the level of 2,3-diphosphoglycerate (2,3 DPG) and ATP in the red cells. The reduced ATP level in the red cells was one of the causes of reduced Ca2+ ATPase activity in their membranes.

[The pharmacological correction of disorders of the oxygen transport function of the blood in peritonitis patients].

Arterial hypoxemia, decrease in non-organic phosphorus, 2,3-DPG, ATP erythrocyte levels and associated deterioration of O2 tissue supply have been observed in 106 patients with peritonitis. Intravenous administration of propranolol, potassium dihydrophosphate and inosine prevented a decrease in erythrocyte phosphate level, improved oxygen and energy tissue supply and reduced the duration of the patient stay in hospital.

[The correction of disorders of phosphorus and calcium metabolism in patients following surgery of the abdominal organs].

In 158 patients operated on the abdominal organs, hypophosphatemia and decrease in the content of ATP, 2,3-DPG in the erythrocytes were revealed. The level of protein-free calcium was increased in the plasma and erythrocytes. This evidenced in favour of the increased ionized calcium content.

[The use of klofelin in general anesthesia during and after surgery of the abdominal organs].

The use of klofelin in general anesthesia of the patients operated on for acute cholecystitis, pancreatitis, appendicitis, gastroduodenal ulcer permitted to normalize hemodynamics, reduce the dosages of the administered phentanyl 1.5-fold, kalipsol--2-fold, promedol after the operation-2.5--fold, contributed to early awakening and activization of the patients, prevention of the development of complications and narcotic dependence after the operation, improvement of the results of treatment.

[Causes, sequelae and possible ways of preventing hypophosphatemia in patients with cerebral ischemia].

Hypophosphatemia revealed in patients with acute disorders of cerebral circulation was one of the causes of a decrease of the content of 2,3-DPG, ATP in red blood cells and of a reduction of Ca2(+)-ATPase activity in red blood cell membranes. In the given group of patients, hypophosphatemia was provoked by complete parenteral feeding, hypocapnia and by loss of phosphorus with urine and congestive gastrointestinal contents.

[Characteristics of phosphorus metabolism in patients with acute disorders of cerebral circulation].

The first 5 days of treatment of 98 patients with acute disorders of the cerebral blood circulation revealed hypophosphatemia and related reduction of the level of 2, 3 DPG, ATP in the erythrocytes. The causes of hypophosphatemia in these patients were absence of entrance of phosphorus to the body, its loss with the urine and gastrointestinal contents and hypocapnia. The possible ways of correction of these disorders are discussed.